Hi, We want a best guess Expected period of survival? Should another blood test (psa) be done immediately...was this a mistake /error? sholud he have any other scans / biopsey? Hi, My father has just had a psa reading of 100 following previous diagnosis and treatment of Prostrate cancer: Facts :My Father is now 78yrs old (76yrs when P.Cancer identified) His Father died of prostrate cancer. Approx middle of 2008: psa 24, gleason 8, T3B TUMOUR DISCOVERED, Treatment given, tablets to reduce size of Prostrate, / reduce hormones and Radiotherapy, 3to4 weeks x5 days. Psa levels dropped to I believe below or about 1, then readings have been 5 in sept 2009, 5 in Nov 2009,12 in Feb 2010,16 in Apr 2010 , 21 in July 2010 and now 100 in Oct 2010. He has had tablets to help water works and whilst leaks a bit at night does not have to get up that often now once or twice as opposed to 6 to 10 previously. No bone aches, feels ok, gets stiff when sat down and struggles to get back up out of chair however had a Full knee replacement in Feb this year, was knocked for six by the General anaesthetic and had full mir scan= all clear as this co-insided with bringing on dementure for which he is recently subscribed tablets (arrisat... sorry cant spell it) which have helped. Due to have his other knee done at some stage. From March 2010 he has been on half tablets and Injections every three months. He has now been prescribe a different hormone treatment drug .... stilbestrol. Main things are should we be checking anything else and what is his best guess life expectancy. (oh when diagnosed with pc, told and i think codes show it was not thought that the cancer had spread into Lymph nodes or bones only, just outside prostrate. Please be as clear and frank as possible in answer we dont, need comfort / wool if you know what I mean.. we just want to plan and make the best use and make Fun the remaining time.... its just how much time? Thank you.