hi thank you for providing the brief history of you. as most medication will have its own side effects and they are on random basis so judging is not possible without any physical examination. As you are having persistent swelling of the ankle, I feel it is lack of venous insufficiency. Also, you are a high BP patient and proceeding towards ageing this is also the factor to keep into consideration. As, in my clinical practice I see geriatrics with high age groups. Many of them have multiple issues and with medication some are not getting relief of swelling. I personally prefer to have a thorough examination and then advice physical therapy and find miraculous changes in the swelling of the ankles. I will advice you to undergo a proper physical therapy where your venous insufficiency can be improved and the swelling can be avoided. Also, venous insufficiency is due to the lack of the venous pool by the Heart which needs an attention. I didn t mean the heart has problem , but I intended to mention that the heart needs more pumping action to reduce the swelling. Regards Jay Indravadan Patel