I have received prolotherapy, prp (which did temporary relieve all pain in my knee, but has since returned), and two stem cell procedures using adipose tissue and spaced a year apart. All this was following arthroscopic surgery, physical therapy and cocks comb injections which provided no relief. The arthroscopic surgery made the knee even worse. After the second stem cell procedure, the pain tripled in severity and the physician instructed me to take three Motrin three times daily. After no relief in pain, he told me to increase the dosage to six Motrin three times daily, but again no relief. During the adipose tissue harvesting, he had an observer present who later left with some of my stem cells, but without my then knowledge or permission. In addition, I see that lidocaine from Hospira that was used might be part of a lot that was infiltrated during manufacture with metallic particles that could lodge in injection sites or be carried to other sites and cause severe pain, stroke, or other adverse effects. I have been complaining about increasing pain at all injection sites (knee, tibia, sole of foot), but have not had any success with resolving the issue. I did receive notice that Hospira manufactured the Lidocaine, there was no record of the lot number and that the facility did not receive a notice that they were part of a recall. I was a self pay patient and all is far worse following my August 2014 treatment than I was before treatment. The doctor said that he is sorry he couldn t help me and has me talking to a nurse who I have not heard from in two weeks. I recented made an appointment with an orthopedist at a nearby tertiary hospital who spent 8 minutes with me. He asked me to tell him what the problem was, never looked at my knee, took new xrays to the tune of $1100 and then stated that he would not operate on my knee. He told me that he was going to have me see another doctor who specialized in spinal surgery (I have a 22 degree curve that does not cause pain). The office staff was not alerted to this when I asked immediately after and told me that I would be called back. This was over two months ago and I am still waiting. I have a consultation with another doctor in June for evaluation for a TJR, but am now using a cane, walker and almost ready for a wheelchair. Before the last stem cell treatment and prp I still was walking without much pain so my hypothesis is that something in the lidocaine must have initiated the pain since every spot injected hurt and continued to and even resulted in a ruptured quadracepts tendon where injected when he tried to even up my posture. I will be calling Hospira to find out whether the bad lots of lidocaine were purchased by the facility that I had the procedure done at and take it from there. What is your perspective of my situation?