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Dr. Andrew Rynne
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Dr. Andrew Rynne

Family Physician

Exp 50 years

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Is Pregnancy Possible In A Woman With High Anti-TPO Level?

Hi Doctor, I m 35 year old married lady had 6 miscarriages. Doctors done almost all tests including karyotyping of both me & my husband. But everything normal. I m a hypothyroid and maintaining TSH level 1-2 by levothyroxin. My anti-TPO is greaterthan 1000 IU. Is this high anti TPO will affect the pregnancy outcome? My endocrinologist is not bothered about the report. If it is a concern, what treatment I should do?
Wed, 7 Jun 2017
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Infertility Specialist 's  Response
Hello and Welcome to ‘Ask A Doctor’ service.
I have reviewed your query and here is my advice.

I think you should get an APLA profile done to find out the cause of recurrent pregnancy losses. You can take Ecosprin, daily injections of heparin and injectable progesterone to support the pregnancy and prevent miscarriages. Talk to your doctor regarding this. High Anti TPO is not a problem for you but it may be the reason of miscarriages. Ecosprin and Heparin will help in preventing that.

Hope I have answered your query. Let me know if I can assist you further.

Regards,
Dr. Khushboo Priya
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Is Pregnancy Possible In A Woman With High Anti-TPO Level?

Hello and Welcome to ‘Ask A Doctor’ service. I have reviewed your query and here is my advice. I think you should get an APLA profile done to find out the cause of recurrent pregnancy losses. You can take Ecosprin, daily injections of heparin and injectable progesterone to support the pregnancy and prevent miscarriages. Talk to your doctor regarding this. High Anti TPO is not a problem for you but it may be the reason of miscarriages. Ecosprin and Heparin will help in preventing that. Hope I have answered your query. Let me know if I can assist you further. Regards, Dr. Khushboo Priya