Hi, Yes, certainly it indicates that person is at a higher risk of heart disease. So you do yearly work up which is negative. So continue with test like Lipid profile, sugars, ecg. Also you can get one treadmill test done. Be vigilant for heart symptoms like chest, back or arm pain or heaviness, sweating, upper abdominal pain, even acidity symptoms. Rush to hospital in case of such problems. You should have a healthy lifestyle like avoiding fatty, oily and high calorie diet. Have low salt diet and monitor blood pressure regularly. Regular exercises like brisk walking, jogging according your capacity at least 30 min a day and 5 days a week. Eat lots of green leafy vegetables, fruits, fish once or twice a week, and avoid meat. Avoid smoking and alcohol if any. There shouldn t abdominal fat deposition or obesity. Hope I have answered your query. Let me know if I can assist you further. Regards, Dr. Sagar Makode