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Dr. Andrew Rynne
MD
Dr. Andrew Rynne

Family Physician

Exp 50 years

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Is It Safe To Take Prednisone During Pregnancy?

hi i am 28 weeks and 3 days pregnant and i am on predison 5mg i take 5 mg one day and 10 mg the next..is it safe for the baby? I started on predison when i was about 15 weeks and havnt stopped taking it since then. its the only thing that helps me with the pain.
Mon, 30 Nov 2015
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OBGYN,  's  Response
Hi,

Yes, if your condition warrants that you take prednisolone, it is fine to take it during pregnancy. Please continue it, as abrupt stopping of the drug can cause harm. Also when you go into labour this oral prednisolone will have to change to injection hydrocortisone drip as, sudden stoppage of prednisolone can cause symptoms of steroid withdrawal, which could complicate delivery, and affect you and the baby.
Prednisolone does not cross the placenta and so minimally affects the baby. It is known to cause very rarely a condition called, cleft palate, where a part of the mouth of the baby is ill developed. But it occurs if taken before 15 weeks and it can be ruled out on the 20 weeks anomaly scan. So if your 20 weeks scan is normal, you have nothing to worry about.

Hope this helps.
Regards.
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Is It Safe To Take Prednisone During Pregnancy?

Hi, Yes, if your condition warrants that you take prednisolone, it is fine to take it during pregnancy. Please continue it, as abrupt stopping of the drug can cause harm. Also when you go into labour this oral prednisolone will have to change to injection hydrocortisone drip as, sudden stoppage of prednisolone can cause symptoms of steroid withdrawal, which could complicate delivery, and affect you and the baby. Prednisolone does not cross the placenta and so minimally affects the baby. It is known to cause very rarely a condition called, cleft palate, where a part of the mouth of the baby is ill developed. But it occurs if taken before 15 weeks and it can be ruled out on the 20 weeks anomaly scan. So if your 20 weeks scan is normal, you have nothing to worry about. Hope this helps. Regards.