Hello Sir, My opinion is that taking Jack3d, a supplement banned in the United States it is so dangerous, you may expect severe problems because not only are you taking a supplement banned from the American markets for causing liver failure and cerebral hemorrhage and combinging it with Wellbutrin (same thing as Chantix) making it a psychoactive drug not to be combined with other drugs or supplements without your physicans approval. I, sir, would not grant that approval. Jack3d is dangerous. My advice: Do not take it or try it. Fish oil,the omega 3s DHA and EPA are very beneficial. If you want a better pump, supplement your diet with the amino acid arginine, 250 mg. vitamin C in the form of a protein shake. Arginine is needed in greater amounts when trying to build extra muscle. In fact, it becomes an essential amino acid when muscle-building is attempted. Thank you for seeking clarification on HCM before you hurt yourself. Best wishes to you. Kathy Shattler, MS,RDN