Hi. Thanks for your query. Noted the history and understood your concerns. This is very tricky as you do not have symptoms but then why were the endoscopies done at all. Well, Nexium helps to neutralize the acid in stomach by proton pump inhibition and Ranitidine helps for the same by its H2 blocker action. Wither of these should help you. Since you have hiatus hernia too, it is not necessary that it gives symptoms unless it is large. So wait and watch is the policy. You can certainly take the medication for 6 weeks and see the results. There may be some improvement for the minor symptoms that you have not noticed but become apparent after a proper management. Also take small frequent meals. Avoid any activities that increase intra-abdominal pressure too much. Also see for any development of new symptoms and report to your Doctor to get investigated and treated accordingly.