Resepcted user, hi sorry to hear about your issue. *As you must be knowing hydrocodone is a semi-synthetic opioid synthesized from codeine, one of the opioid alkaloids found in opium poppy. *Currently now it`s not helping much has various reasons : - body`s acceptance to certain dose levels , diminishing its intensity of pain relief. - progress of neurological ailments . - concurrent use of alcohol / smoking / other anti-depressent or CNS affecting molecules . - decreased pain threshold of the body with increasing age / generalised debility. @ Conclusion : Hydrocodone is right medicine for you along with which you have to take certain extra measures for better relief : - avoid smoking / alcohol / any abuse substances if used. - have adequate sound sleep of 8 hours. - do regular exercises at home including YOGA. - try to remain ambulatory till possible. - avoid excess use of pain killers ultimately going to damage your kidneys on long term basis. - try to accept certain limitations of body as many neurologies are irreversible & untreatable unfortunately. - try to divert your mind in your liked activities more. - concurrent use of other molecules should be strictly under guidance of your neurologist only. - maintain your hydration , BP , Blood sugar & Cholesterol levels in control - maintain your weight. - have diet rich in protein , iron , vitamins , minerals, anti-oxidants to boost up your immunity. Hope this clears your query. Thanks for using Health Care magic & keeping trust in our medical services. Wishing you a very happy healthy life ahead. Regards dear take care.