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Dr. Andrew Rynne
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Dr. Andrew Rynne

Family Physician

Exp 50 years

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Is Ashwagandha Supplement Effective In The Treatment Of Adrenal Fatigue?

As long as it is free, I will ask. If not, forget it. I have no funds to pay for anything at the moment. I would like to know why Ashwaganda is sometimes used to treat adrenal fatigue when I have read that one of its side effects is that it can actually LOWER cortisol. With adrenal fatigue you need to INCREASE the cortisol, not reduce it. Can you explain that to me, please? Many thanks.
Tue, 28 Nov 2017
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General & Family Physician 's  Response
Ashwagandha For Adrenal Fatigue

Ashwagandha or Withania somnifera, a popular ayurvedic herbal remedy, is a powerful antioxidant and anti-stressor. Could ashwagandha – also known as Indian ginseng and used for a range of ailments and disorders – be tapped for treating your adrenal fatigue issue? The answer might well be a resounding yes.

Ashwagandha is already a celebrated treatment for stress, anxiety, and even depression. Its role in regulating stress-hormone cortisol levels in the body has made it a popular “adaptogen.” Adaptogens help improve and speed up recovery from stress. So when ingested, it can act to raise cortisol levels when they are low and lower cortisol when it feels levels are too high. Besides acting as a normalizer, it also improves your resistance to a range of biological as well as chemical and physical stressors. Studies on animal subjects show that it can counter the effects of changes in adrenal weight and cortisol levels associated with extreme stress.


Separate studies on rats also revealed the ability of Withania somnifera to help boost stamina in swimming endurance tests. It also prevented the adrenal glands from producing cortisol and ascorbic acid under this stress. Due to the stress from chronic swimming, the animals had lowered levels of glutathione (GSH) and saw lipid peroxidation. Further, antioxidant defense enzyme levels also dipped. But when the herbal remedy was administered, their GSH levels were restored and lipid peroxidation also declined. Researchers inferred that oxidative stress had a critical part to play in chronic fatigue, making antioxidants like Indian ginseng a good line of treatment.

Mounting evidence also shows the effectiveness of ashwagandha in treating adrenal fatigue-related issues. In one study of chronically stressed individuals, those who took Withania Somnifera saw their modified Hamilton anxiety scores, cortisol levels, pulse rates, blood pressure, and C-reactive protein levels decrease significantly compared to those who were on a placebo.

By helping you cope better with stress and normalizing your condition when you stress out, the herbal remedy is in effect doing what your “exhausted” adrenal glands are no longer doing.

Side Effects Of Ashwagandha:

While ashwagandha has been widely used in Ayurveda for centuries to treat stress and fatigue problems, it’s a herb that needs to be used with caution. Like any herbal remedy or medication, it needs to be taken at prescribed levels as recommended by a herbal medicine or naturopathy specialist or Ayurvedic practitioner. Up to 4 gm a day is generally safe, and side effects like stomach upsets or abdominal discomfort are typically seen only for larger doses of 10 gm and over.
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Is Ashwagandha Supplement Effective In The Treatment Of Adrenal Fatigue?

Ashwagandha For Adrenal Fatigue Ashwagandha or Withania somnifera, a popular ayurvedic herbal remedy, is a powerful antioxidant and anti-stressor. Could ashwagandha – also known as Indian ginseng and used for a range of ailments and disorders – be tapped for treating your adrenal fatigue issue? The answer might well be a resounding yes. Ashwagandha is already a celebrated treatment for stress, anxiety, and even depression. Its role in regulating stress-hormone cortisol levels in the body has made it a popular “adaptogen.” Adaptogens help improve and speed up recovery from stress. So when ingested, it can act to raise cortisol levels when they are low and lower cortisol when it feels levels are too high. Besides acting as a normalizer, it also improves your resistance to a range of biological as well as chemical and physical stressors. Studies on animal subjects show that it can counter the effects of changes in adrenal weight and cortisol levels associated with extreme stress. Separate studies on rats also revealed the ability of Withania somnifera to help boost stamina in swimming endurance tests. It also prevented the adrenal glands from producing cortisol and ascorbic acid under this stress. Due to the stress from chronic swimming, the animals had lowered levels of glutathione (GSH) and saw lipid peroxidation. Further, antioxidant defense enzyme levels also dipped. But when the herbal remedy was administered, their GSH levels were restored and lipid peroxidation also declined. Researchers inferred that oxidative stress had a critical part to play in chronic fatigue, making antioxidants like Indian ginseng a good line of treatment. Mounting evidence also shows the effectiveness of ashwagandha in treating adrenal fatigue-related issues. In one study of chronically stressed individuals, those who took Withania Somnifera saw their modified Hamilton anxiety scores, cortisol levels, pulse rates, blood pressure, and C-reactive protein levels decrease significantly compared to those who were on a placebo. By helping you cope better with stress and normalizing your condition when you stress out, the herbal remedy is in effect doing what your “exhausted” adrenal glands are no longer doing. Side Effects Of Ashwagandha: While ashwagandha has been widely used in Ayurveda for centuries to treat stress and fatigue problems, it’s a herb that needs to be used with caution. Like any herbal remedy or medication, it needs to be taken at prescribed levels as recommended by a herbal medicine or naturopathy specialist or Ayurvedic practitioner. Up to 4 gm a day is generally safe, and side effects like stomach upsets or abdominal discomfort are typically seen only for larger doses of 10 gm and over.