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Dr. Andrew Rynne
MD
Dr. Andrew Rynne

Family Physician

Exp 50 years

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How Should Mifepristone Be Taken?

I am about to be five week pregnant and am told to take one mifepristone pill after breakfast orally, and on the next day two misoprostol pills after breakfast, and then two again after lunch, all to be taken orally. Please tell if it is the right way to do so? What is the correct method of orally taking the pills, should I swallow it or to be kept under tongue? Is it okay to take after light meals or should be taken on empty stomach?
Mon, 4 Dec 2017
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Anesthesiologist 's  Response
hi mam,let me tell you the administration in detail.
1)first take 200mg of mifepristone orally after breakfast.
2)then after 24hrs and before 48hrs,you need to take 800mcg(4 tablets each 200mcg) of misoprostol.
3)keep 2 tablets of misoprostol each 200mcg in the cheek pouch(space between the cheek and gums) of both sides for 30 min.then you can swallow the remnants with water.this is to be repeated with 2 more tabs of misoprostol 200mcg each in both the cheek pouches after lunch.
CAUTION : most women expel the uterine contents in 2-24hrs after taking misoprostol.so,be prepared for that or stay indoors.also you may experience abdominal cramps during expulsion after taking misoprostol.
hope i'm clear in my explanation.still if you have any queries,please let me know.i'm always ready to assist and guide.thank you.take care.bye.
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How Should Mifepristone Be Taken?

hi mam,let me tell you the administration in detail. 1)first take 200mg of mifepristone orally after breakfast. 2)then after 24hrs and before 48hrs,you need to take 800mcg(4 tablets each 200mcg) of misoprostol. 3)keep 2 tablets of misoprostol each 200mcg in the cheek pouch(space between the cheek and gums) of both sides for 30 min.then you can swallow the remnants with water.this is to be repeated with 2 more tabs of misoprostol 200mcg each in both the cheek pouches after lunch. CAUTION : most women expel the uterine contents in 2-24hrs after taking misoprostol.so,be prepared for that or stay indoors.also you may experience abdominal cramps during expulsion after taking misoprostol. hope i m clear in my explanation.still if you have any queries,please let me know.i m always ready to assist and guide.thank you.take care.bye.