Misoprostol

What is Misoprostol?

Misoprostol is a medication used to start labor, induce abortions, prevent and treat stomach ulcers, and treat postpartum bleeding due to insufficient contraction of the uterus. or methotrexate.

Common side effects include diarrhea and abdominal pain. It is pregnancy category X meaning that it is known to result in negative fetal outcomes if taken during pregnancy. Uterine rupture may occur.

It is on the World Health Organization's List of Essential Medicines, the most important medications needed in a basic health system. Misoprostol was invented and marketed by G.D. Searle & Company (now Pfizer) under the trade name Cytotec, but other trade names and generic formulations are available.

Questions and answers on "Misoprostol"

What happens if 25 mcg of misoprostol is taken by mouth every 8 hours for three doses? What happens if 25 mcg of misoprostol is taken by mouth every 8 hours for three doses?

doctor1 MD

Hi,
Please dont take hormones without medical supervision.Misoprostol can cause bleeding and if taken at the wrong time without medical advice,then there may be more serious complications.

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I have 10 weeks pregnency by LMP and ultrasound shows 6 weeks 4 days. I did 2 ultrasound with difference of 10 days. But there is no growth in fetus . My Gyno suggested me to abort it and I am using Mankind Unwanted KIT. I took 200mg of Mifepristone tab 20 hrs before but no bleeding till now Can I take 400mg of Misoprostol now or take it only after 48 hrs?

doctor1 MD

Hello,
Misoprostol is best effective if it is used 48 hours after taking mifepristone. Hope you have taken the total dose prescribed by your doctor. It is usually used within 49 days of pregnancy and rarely after that in some occasions. As per your ultrasound report you are suffering from missed...

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hi - i had some sexual encounter (not sex, just fingering) 2 months ago. i had 2 normal but light periods on time. this month i am late. i haven't taken a pregnancy test but am 3 days late on my period. i took 400mg of misoprostol under my tongue and 4 hours later experienced light bleeding - somewhat like heavy spotting. 12 hours later this has stopped. would i still have bled if i was not pregnant? what would have happened if i took the misoprostol while i was not pregnant? could it kick-start my period?

doctor1 MD

Hi,
Misoprostol initiates uterine contractions as it contains prostaglandin; so even without pregnancy it can cause some amount of spotting or bleeding along with cramps. It is always advisable to initiate treatment under the guidance of a specialist after the presence of an intra-uterine...

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Im on my six weeks pregnancy and I had taken mifepristone on 2 March and yesterday I had taken 2 tablets of misoprostol but there was only normal bleeding, no pains. Again I took 2 tablets of misoprostol today till now no sign of pains or heavy bleeding. Can u please help me with this

doctor1 MD

Hi,

Thanks for writing to us.

Kindly wait for a week or ten days for the drugs to act. They will take some time to work and cause bleeding. Please do not take any more tablets. After the bleeding is over please take an ultrasound scan to see if the uterus is emptied. In case if you still do not...

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Dr i want to do abortion myself and my fetus is 2.5 months, i have the mifepristone tablet and misoprostol tablet i can't consultate with the Dr because where i live is for a way from the health center, i need online information that would be better if i could get any information what i am doing,

doctor1 MD

Hello
Thanks for writing to us with your health concern.
Do not attempt to try and abort the pregnancy by yourself.
It can have life threatening implications, under no situation should you attempt such a dangerous stunt by yourself.
Luckily, early pregnancy can be terminated by medications,...

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Hello, My LMP was 13th Feb 2012, then I had intercourse with my husband on 26th Feb, We did UPT on 4th March it was negetive, then we did it again on 18/03/2012,then also it was negetive but when we repeated it on 24th March there was a dark pink line and one fain line..we asked a doctor friend a she told us that it is a positive sign so we then decided to go for MTP through MTP kit, I took 600 Mg of Mifepristobne yesterday morning but later in evening I developed severe abdominal pain and the today morning I started bleeding vaginally...is it normal or we shall seek a medical attention, do we still need to take the misoprostol dose which is due tomorrow morning, what will happen...kindly tell me...I am affreaid..wht precautions we should take or any other advise from you..

doctor1 MD

HI
THE MEDICINE U R TAKING SHOULD BE TAKE UNDER MEDICAL GUIDANCE.
SOME AMOUNT OF BLEEDING IS OUGHT TO BE THERE.
IF BLEEDING HEAVILY...PLZ VISIT UR GYNAEC....
DO A BASIC USG SCAN TO RULE OUT ECTOPIC PREGNANCY TOOO.
BEFORE TAKING MISOPROSTOL IT WILL BE GOOD TO SEEK MEDICAL ADVISE......

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doctor i am in 4th week of pregnancy. i have taken 800 mg misoprostol yesterday. 2 tablets in morning and 2 in the night orally. bt still bleeding is not started. my abdomenal muscles contract and some liquid comes out through vagina..bt bleeding is not come? what can i do now?

doctor1 MD

Hello dear
understand your concern
Misoprostol should be taken under the guidance and observation of gynecologist. Ideally 800 ug misoprostol should be taken vaginally/orally maximum up to 3 dose at 6 hourly interval under the observation of gynecologist. Normally bleeding will start with in 1-2...

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my wife miens in december 27 but not in that time i am check mainkind kit and result positive in January 12 and give a 2 Misoprostol tablet therefore mens naturally in to days but after 3day the bleeding stop . in that time i am not sex to my wife , but in February 17 my wife is not mens ,in that am check kit then positive result. then i am give a 2 Misoprostol tablet therefore mens naturally in to days but after 3day the bleeding stop . then i am not sex my wife but m=in march 31 same reason what is the problem

doctor1 MD

Hi,
Thanks for writing to us.
Sometimes pregnancy test may be positive after abortion also.
You should get her ultrasonography test done to rule out pregnancy first.
Please do not give her so many misoprostol tablet.
It may be harmful to her.
Good luck.
Regards
Dr....

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Recent questions on  Misoprostol

doctor1 MD

Dear Sir/Mam, I am married working women.Always my periods was regular this time, still it was not happened, so i took the Kit of Mifepristone & Misoprostol tablets. Yester morning i eat Mifepristone tablet & rest of 4 Misoprostol tablets were took in yesterday 2.30 pm 1 tablet, 9pm 1 tablet & today morning 1 & now 1 tablet i eat. My doubt is can we eat this tablet or not, if eat means we will any problem.

doctor1 MD

i am 3 weeks pregnant but i took a cytotec a misoprostol 250mg tablet. I am so sorry but i need to. this is my very first time to get pregnant. I was so worried and i already 1 week when i took the tablet. I had blood yes since that happened dec.27,2010 when i decided to take the tablet at 8pm then early around 6am i had a blood already till i reach 7 days more. Is it dangerous for me if i am not going to doctor anymore for a check up or special treatment?

doctor1 MD

Hi my name is lakshmi from Chennai. My age is 25 yrs and i m pregnant for since last 1 and a half months. But now i want to terminate my pregnancy. I had been took Misoprostol last night but till now i did not have bleeding... Please suggest me the right name of the pill to abort pregnancy and the procedure to take the pill...

doctor1 MD

Hello Doctor. My wife took 200 mg of mifepristone on May 30 followed by 200 mg of misoprostol on June 1. She is to take four misoprostol tablets more. She is in the elementary stage of pregnancy. No signs of bleeding so far. Is the medicine not working. She is quite worried. Pls advise. My wife is 38 yrs, 5 ft, 50 kg.

doctor1 MD

Hello Doctor, My wife's period date was Aug 28, 2013, Her next period date should have been somewhere at the end of September which didn't occur. When we took pregnancy test the result came as positive. We don't want to have a baby now as we...

doctor1 MD

I have taken mifegest kit ten days ago .but the symptom and pregnancy test kit, in which one dark and other faint line appeared, indicte for incomplete abortion .now what shhould I do .may I take misoprostal tab again for complete abortion.

doctor1 MD

I HAVE 5 WEEKS PREGNANCY . I HAVE TAKEN ONE TABLET OF Miferpristone Tablet. I just want to know that after how much time i can take second dose of two Misoprostol tablets and third dose of two Misoprostol Tablets.

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Dr. Andrew Rynne
MD

Hi, I am Dr. Andrew Rynne (Family Physician). I will be guiding you through the process. Please write your question below.

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