I have been taking Luvox since 1987. It treated my OCD and major depression for many years. For the last seven or eight years, my depression started up again. Now is is a major depression. I have lost my husband, my father and two close friends in less than 4 years, but the depression started before they died. I almost lost my daughter, who has Type 1 diabetes. She was dead, but the third time they were able to bring her back. They put her in a coma for over a week using Propopol. I have it in the back of my mind that I could lose her again. My doctor doesn t seem to think there are other meds I can use for my depression. I am barely coping, have no family, except for my daughter. I hang on only for her and my lab. My question is: What suggestions do you have for treating my depression that will not bring bring my OCD back? I tried ketamine, but it did not help at at and was quite expensive. My doctor has left my twisting in the wind. She put me on Zoloft, but I had horrible nightmares. Maybe it was because I took the Zoloft before I went to bed. Can you suggest something for the Major Depression, without the OCD coming back, too? Thank you. Claudia EMAIL ADDRESS: YYYY@YYYY