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Dr. Andrew Rynne
MD
Dr. Andrew Rynne

Family Physician

Exp 50 years

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High Blood Pressure, Urticaria, Hives, Have Headaches, Fatigue And Low Energy Level. Prescribed Coversyl. What Is The Reason?

I am a fit and healthy 45 year old female except that I have been hypertensive since my mid-twenties inherited from both my mother and father. Initially I started on Karveside, then went on to Atacand and then finally on Atacand Plus for many years which seemed to work well keeping me to 140/90. However, recently when I saw my Dermatologist about ongoing urticaria and hives he suggested that I try another type of medication for my high blood pressure as he believes it may be contributing to my skin rashes. Consequently my GP prescribed me Coversyl Plus 2.5mg/0.625mg which was not working and my BP was up to 196/133, so 9 days ago I went back to her and she merely doubled my dose of Coversyl Plus to 5mg/1.25mg. This still is not doing much as I am still averaging about 170/110 which seems too high. Moreover in the last 5 days I have been experiencing bad headaches, referred neck and back of head pain, low energy and fatigue. My Dr told me to give it a fortnight before going back to her but I have already taken two days off work and feel really off. Any thoughts from you would be appreciated. Cheers Jennifer
Mon, 14 Oct 2013
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General & Family Physician 's  Response
Hello,
Thanks for the query to H.C.M. Forum.
Previously you were using atacand plus i.e. candesartan + hydrochlorothiadize and this drug developed allergic reaction . These allergic reaction are side effect of this drug.
This drug is ANGIOTENSIN 2 receptor blockers i.e. the group of this drug is different. This was a reason that this drug was acting very well .
Coversyl ( perindopril ) is an ACE inhibitors and this drug in my opinion is a drug of different group , that is the reason that this is not working in your case .
In such type of situation I prescribe telmisartan + hydrochlorothiazide .
Although telmisartan also causes sinusitis but not too serious . Telmisartan rarely causes urticaria and rashes , so you can use this drug after consultation with your treating doctor.
Good luck. Dr. HET
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High Blood Pressure, Urticaria, Hives, Have Headaches, Fatigue And Low Energy Level. Prescribed Coversyl. What Is The Reason?

Hello, Thanks for the query to H.C.M. Forum. Previously you were using atacand plus i.e. candesartan + hydrochlorothiadize and this drug developed allergic reaction . These allergic reaction are side effect of this drug. This drug is ANGIOTENSIN 2 receptor blockers i.e. the group of this drug is different. This was a reason that this drug was acting very well . Coversyl ( perindopril ) is an ACE inhibitors and this drug in my opinion is a drug of different group , that is the reason that this is not working in your case . In such type of situation I prescribe telmisartan + hydrochlorothiazide . Although telmisartan also causes sinusitis but not too serious . Telmisartan rarely causes urticaria and rashes , so you can use this drug after consultation with your treating doctor. Good luck. Dr. HET