Hello, I recently (three months) began to receive injections of xolair once a month for treatment of my asthma and allergies. It has helped greatly to reduce my inhaler use but ever since taking it I have had pain slowly increasing in an ankle that I had broke about 10 years ago. Two days ago the pain became so severe that I literally thought I may have broke it again. I had to use crutches and I began to take o.t.c. tylenol and ibuprophen in order to be able to even go to work today. Have you had any other people complain of pain this severe that are receiving xolair? I do plan on seeing my Dr. as soon as I can get an appt. I would appreciate your advice and input! Thank You!