hello, your mother is on steroid and has developed depression and was put on zapiz. then she developed regurgitation. Now you suspect zapiz for the same. First- steroid, when given for longtime - can cause depression and many other psychiatric disorders. ( it is seen very commonly in clinical practice). second: zapiz is not a drug which she should be given, for it is just a sedative and not an anti depressant. Your mother should revive something like~ sertraline/ escitalopram etc. Third- the egurgitaion appears to be due to reflux, which is most probably related to steroid use and not zapiz. Zapiz dose not cause this thing commonly. However, another psosibilty can be beacsue of depression/ anxiety. So, I would sincerely advice you should talk to a psychitrist in detail about your mother. Hope the reply is useful please feel free to ask more questions Dr. Manisha Gopal MD. psychiatry