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Dr. Andrew Rynne
MD
Dr. Andrew Rynne

Family Physician

Exp 50 years

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Does Lyrica Cause Aggressive Behaviour And Irritability?

My 17 year old daughter started taking lyrica about 6 months ago. She started with 25mg before bed and over time gradually increased to 100mg nightly. While it s never really helped with the pain, it did help with her sleep problems. However, I would say that since she started the 75mg and then the 100mg dose, she has become extremely irritable, angry and completely lost interest in school. She went from A s and B s in what were mostly AP classes, to D s and F s. she is in real jeopardy of not graduating and doesn t seem to care. She actually says she s fine just living in her car. She s received several acceptance letters to college and after thinking it was perhaps a burnout phase, I m actually thinking this could be the lyrica because it s so out of character. We have an appointment with her DR in a couple weeks, but really I want to get her off of this. What would be the best method? I m already thinking she hasn t been taking it as regularly as she was supposed to because she s been complaining of severe headaches and gi issues.
Fri, 23 Nov 2018
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General & Family Physician 's  Response
Hello, Welcome to Ask a doctor services. I have read your query. Side effects of Lyrica(Pregabalin) can cause difficulty in focus/concentration & sometimes co-ordination leading to irritability. Stupor, loss of balance or co-ordination, problems with memory can cause disinterest in studies & in day today life. These may complicate to anxiety or depression related problems, ultimately leading to suicidal thoughts.

Report the symptoms to the treating doctor so that either the medications can be altered or doses reduced. She should take adequate rest & stay away from addictions if any. Alcohol & medications that cause sedation can trigger the side effects cause discomfort & restlessness. Hope I have answered your query. Take care.
Regards,
Dr Nupur K
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Does Lyrica Cause Aggressive Behaviour And Irritability?

Hello, Welcome to Ask a doctor services. I have read your query. Side effects of Lyrica(Pregabalin) can cause difficulty in focus/concentration & sometimes co-ordination leading to irritability. Stupor, loss of balance or co-ordination, problems with memory can cause disinterest in studies & in day today life. These may complicate to anxiety or depression related problems, ultimately leading to suicidal thoughts. Report the symptoms to the treating doctor so that either the medications can be altered or doses reduced. She should take adequate rest & stay away from addictions if any. Alcohol & medications that cause sedation can trigger the side effects cause discomfort & restlessness. Hope I have answered your query. Take care. Regards, Dr Nupur K