Yes, I am wanting to know if exemestane can cause weight gain and water retention? I am recovering from breast cancer and am overweight (195#and 5 tall) . Currently I am taking : exemestane 25mg, naproxen 500mg, aspirin 81mg, tofranil 30mg, raloxifene 60mg, hydrochlorothocide 25mg, amlodipine benazepril 10-20mg, omeprrazole 20mg, and effexor 37.5mg. I also take extra calcium, multi vitamin. Quite a litany I know. I try to eat a healthy diet, but don t have the ambition to cook very often. Being a widow, I don t often get the ambition to make a meal . I am also seeing a chiropractor for an ongoing sciatic issue, so the exercise has dropped off. Any information would be appreciated. Thank you, Annette Downs