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Dr. Andrew Rynne
MD
Dr. Andrew Rynne

Family Physician

Exp 50 years

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Can Rehab Medications Cause Any Wrong Results In The Blood Test?

My daughter has been in a rehab facility that does random UA s. She is taking gabapentin (1200 to 1800mg/daily), ibuprofen (600mg/ 3xdaily), tylenol (325mg/3xdaily). When she went through detox (about 3 1/2 wks ago) she was prescribed lorazepam as well as diazepam. Her UA tested positive for oxazepam (139ng/ml). She insists that she has not taken anything but the above listed medications since entering detox. My question is: will any of the above medications show a positive for oxazepam in a UA? Please help! She has been evicted from the rehab facility and cannot come back until this is resolved. Thank you, More than concerned Dad
Tue, 4 Aug 2015
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General & Family Physician 's  Response
Hello Sir,

I understand your concern.

The question you ask stands; Oxazepam is an active metabolite formed during the breakdown of diazepam and certain similar drugs.
Urine toxicology reports of daily or frequent diazepam users will most likely indicate the presence of all three metabolites of diazepam: nordazepam, temazepam and oxazepam.
As the end product of diazepam metabolism, oxazepam often is present at slightly higher concentrations in the urine than nordiazepam and temazepam. Thus, oxazepam often remains detectable in the urine for a day or two after the other metabolites have been fully eliminated. If patients are drug tested several days after their last dose of diazepam, it is not uncommon to detect only trace levels (
Hope I answered to your question. If you have further concerns, please feel free to ask.
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Can Rehab Medications Cause Any Wrong Results In The Blood Test?

Hello Sir, I understand your concern. The question you ask stands; Oxazepam is an active metabolite formed during the breakdown of diazepam and certain similar drugs. Urine toxicology reports of daily or frequent diazepam users will most likely indicate the presence of all three metabolites of diazepam: nordazepam, temazepam and oxazepam. As the end product of diazepam metabolism, oxazepam often is present at slightly higher concentrations in the urine than nordiazepam and temazepam. Thus, oxazepam often remains detectable in the urine for a day or two after the other metabolites have been fully eliminated. If patients are drug tested several days after their last dose of diazepam, it is not uncommon to detect only trace levels ( Hope I answered to your question. If you have further concerns, please feel free to ask.