Hi there, Welcome to HCM, The above medication are anti epileptics and your wife needs to see a neurologist urgently to see if she is getting the correct dosage and medications. During pregnancy we try to decrease the different anti epileptics to one, if her condition is stable and she has not has a seizure for the last year. This is because the chances of deformities in the baby due to the medication decrease if she takes only one rather than multiple medications. Also she needs to take folic acid 5 mg daily to prevent damage to neural tube. Both epilepsy and its medication can affect the baby, but it is important that her seizures are in control as if she has a repeat seizure during pregnancy that in itself could be more detrimental to the baby than the medication. She will need a detailed anomaly scan at 20 weeks with special attention to fetal heart. And also she need to be seen by a senior obstetrician in a tertiary care center and by a neurologist throughout the pregnancy. Hope this helps. Regards.