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Dr. Andrew Rynne
MD
Dr. Andrew Rynne

Family Physician

Exp 50 years

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Can Long Term Use Of Anatrozole Cause Bronchiolitis Oblterans Organizing Pneumonia?

Well, I just had a CT Scan showing I have Bronchiolitis Oblterans Organizing Pneumonia! I have taken Anastrozole for 31/2 yrs now since I had breast cancer and bilateral mastectomy...could Anastrozole have contributed to this new diagnosis of this BOOP?
Tue, 24 Jan 2023
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General & Family Physician,  's  Response
Hello,

You have history of having breast cancer treated by the prescription medicine, Anastrozole for more than 3 years. Presently, you got a CT done, it shows bronchiolitis obliterans organizing pneumonia. Long term use of any medicine causes adverse effects. You are suggested to talk to your treating doctor, it can be a side effect of the medicine taken for a longer period.

Research studies have shown that aromatase inhibitor in Anastrozole causes decrease in estrogen level and may induce liver, lung, shortness of breath, numbness, etc. Get clinically examined to rule out pulmonary nodules and any fungal infection. Your treating doctor may suggest a biopsy done, get it done so that pathology is detected and treatment started at the earliest. Avoid stress. Stay away from addictions if any. Get it treated at the earliest.

Take care. Hope I have answered your question. Let me know if I can assist you further.

Regards,
Dr. Nupur K., General & Family Physician
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Can Long Term Use Of Anatrozole Cause Bronchiolitis Oblterans Organizing Pneumonia?

Hello, You have history of having breast cancer treated by the prescription medicine, Anastrozole for more than 3 years. Presently, you got a CT done, it shows bronchiolitis obliterans organizing pneumonia. Long term use of any medicine causes adverse effects. You are suggested to talk to your treating doctor, it can be a side effect of the medicine taken for a longer period. Research studies have shown that aromatase inhibitor in Anastrozole causes decrease in estrogen level and may induce liver, lung, shortness of breath, numbness, etc. Get clinically examined to rule out pulmonary nodules and any fungal infection. Your treating doctor may suggest a biopsy done, get it done so that pathology is detected and treatment started at the earliest. Avoid stress. Stay away from addictions if any. Get it treated at the earliest. Take care. Hope I have answered your question. Let me know if I can assist you further. Regards, Dr. Nupur K., General & Family Physician