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Dr. Andrew Rynne
MD
Dr. Andrew Rynne

Family Physician

Exp 50 years

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Can Oxybutinin Be Taken Instead Of Vesicare?

i ve been taking 10 mg vesicare daily. it seems to be less effective the last month or so. can i switch to oxybutinin for awhile to see if it is more effective. I used to take oxybutinin when needed- now i need the medication every day Also I was taking 5 mg vesicare and when it became less effective i began taking 10 mg now as I said above the 10 mg do not do the job anymore.,
Wed, 17 Sep 2014
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Internal Medicine Specialist,  's  Response
Hi,

Thank you for your query. I can understand your concerns.
Oxybutynin, an anti-cholinergic drug is used to relieve urinary and bladder difficulties, including frequent urination and inability to control urination (urge incontinence), by decreasing muscle spasms of the bladder.ADULTS (immediate-release tablet )dose: PO 5 mg twice a day to thrice a day (max, 5 mg four times a day).
Vesicare (solifenacin succinate) is a muscarinic receptor antagonist,used also for overactive bladder with symptoms of urgency, frequency, and leakage. The recommended dose of vesicare is 5 mg once daily,increase to 10 mg once daily if needed.
Both the drugs have similar actions;since drug efficacy may differ you can take Oxybutinin in place of Vesicare in standard doses as mentioned.

Regards

Dr. T.K. Biswas M.D.
Mumbai
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Can Oxybutinin Be Taken Instead Of Vesicare?

Hi, Thank you for your query. I can understand your concerns. Oxybutynin, an anti-cholinergic drug is used to relieve urinary and bladder difficulties, including frequent urination and inability to control urination (urge incontinence), by decreasing muscle spasms of the bladder.ADULTS (immediate-release tablet )dose: PO 5 mg twice a day to thrice a day (max, 5 mg four times a day). Vesicare (solifenacin succinate) is a muscarinic receptor antagonist,used also for overactive bladder with symptoms of urgency, frequency, and leakage. The recommended dose of vesicare is 5 mg once daily,increase to 10 mg once daily if needed. Both the drugs have similar actions;since drug efficacy may differ you can take Oxybutinin in place of Vesicare in standard doses as mentioned. Regards Dr. T.K. Biswas M.D. Mumbai