Oh please do not get these injections and yes it may have an effect on your myoma. Human Chorionic Gonadotropin is a hormone produced during pregnancy. Companies that sell it in the U.S. are breaking the law. The severe daily calorie restriction that the HCG diet calls for is so restrictive that it puts the user at risk for gallstone formation, irregular heart rhythm (can cause stroke), and an imbalance of electrolytes. Side effects: fatigue,irritability,depression, restlessness,fluid build up and blood clots. The best bet for weight loss is the healthy one. If you need a referral, let me know and I can refer you to a dietitian or e clinic for help. Thank you for coming to HCM for some guidance and direction. I hope I have been helpful. Kathryn Shattler, MS,RDN