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Dr. Andrew Rynne
MD
Dr. Andrew Rynne

Family Physician

Exp 50 years

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Are There Any Negative Interactions Between Naproxen, Amlodipine And Lisinopril?

My neighbor is taking Naproxen, Amlodipine, & Lisinopril together . His wife is concerned about his behavior since taking these meds. Are there harmful side effects of any of these meds or any negative interaction between them? He also drinks at times.
Sat, 28 Apr 2018
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General & Family Physician 's  Response
Hello,

It is not safe to take Naproxen medicine while on Amlodipine and Lisinopril drugs.

Taking Naproxen along with Amlodipine and Lisinopril may cause your blood pressure to increase. In addition, Naproxen may affect your neighbor's kidney function, especially when it's used along with Lisinopril for a long period of time.

He may need a dose adjustment or more frequent monitoring of his blood pressure by your doctor to safely use both medications.

Your neighbour should also avoid consuming beer while taking Naproxen, because alcohol can increase the risk of stomach bleeding caused by Naproxen.

Hope I have answered your query. Let me know if I can assist you further.

Regards,
Dr. Mohammed Taher Ali
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General & Family Physician Dr. Mohammed Taher Ali's  Response
Hello,

Yes, harmful interactions can occur if these medications are taken together.

If Naproxen medicine is taken along with Amlodipine drug, this combination may cause your neighbour's blood pressure to increase.

If Naproxen is taken along with Lisinopril, it may reduce the effects of Lisinopril in lowering blood pressure. In addition, these medications may affect the kidney function, especially when they are used together for a long period of time.

He may need a dose adjustment or more frequent monitoring by your doctor to safely use both medications.

Besides, drinking alcohol can increase the risk of stomach bleeding caused by Naproxen hence this should be avoided.

Hope I have answered your query. Let me know if I can assist you further.

Regards,
Dr. Mohammed Taher Ali
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Are There Any Negative Interactions Between Naproxen, Amlodipine And Lisinopril?

Hello, It is not safe to take Naproxen medicine while on Amlodipine and Lisinopril drugs. Taking Naproxen along with Amlodipine and Lisinopril may cause your blood pressure to increase. In addition, Naproxen may affect your neighbor s kidney function, especially when it s used along with Lisinopril for a long period of time. He may need a dose adjustment or more frequent monitoring of his blood pressure by your doctor to safely use both medications. Your neighbour should also avoid consuming beer while taking Naproxen, because alcohol can increase the risk of stomach bleeding caused by Naproxen. Hope I have answered your query. Let me know if I can assist you further. Regards, Dr. Mohammed Taher Ali