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Are There Any Interactions Between Lisinopril And Sulfamethoxazole/Trimethoprim?
HELLO, i m Dan ,GOT A QUESTION, i m on lisinopril 40mg, hydrochlorathiazide 25mg,&carvedilol 25mg for blood pressure & i got an upper respiratory sinus thing going on feels like bronchitus coming back on me again I had it back once in 2014 & in 2015 again once not this year 2016 at all til now same kinda symptoms similar to those & I have this antibiotic it s called Sulfamethoxazole/Trimethoprim 800/160 double strength & I ve never taken this type of antibiotic before so just wondering if there are any side effects or interactions with this with my blood pressure meds??? meds???
Mon, 2 Jan 2017
Hello and welcome to ‘Ask A Doctor’ service.
I have reviewed your query and here is my advice.
Yes, Trimethoprim can cause harmful interaction if taken along with Lisinopril. The antibiotic combination of sulfamethoxazole and trimethoprim is commonly used to treat urinary tract infections, upper respiratory infections like sinusitis, middle ear infections (otitis media), bronchitis, traveler's diarrhea, and shigellosis (bacillary dysentery). Taking Trimethoprim along with lisinopril may increase potassium levels in the blood (hyperkalemia) which in severe cases can lead to kidney failure, muscle paralysis, irregular heart rhythm, and cardiac arrest.
You may be more likely to develop hyperkalemia while using these medications if you are elderly, dehydrated, have kidney disease, diabetes, or advanced heart failure. So, in view of the above, avoid taking Trimethoprim along with Lisinopril. Consult your treating doctor for an alternate effective but a safer antibiotic for the treatment of sinusitis.
Hope this answers your query. Let me know if I can assist you further.
Regards,
Dr. Mohammed Taher Ali
I have reviewed your query and here is my advice.
Yes, Trimethoprim can cause harmful interaction if taken along with Lisinopril. The antibiotic combination of sulfamethoxazole and trimethoprim is commonly used to treat urinary tract infections, upper respiratory infections like sinusitis, middle ear infections (otitis media), bronchitis, traveler's diarrhea, and shigellosis (bacillary dysentery). Taking Trimethoprim along with lisinopril may increase potassium levels in the blood (hyperkalemia) which in severe cases can lead to kidney failure, muscle paralysis, irregular heart rhythm, and cardiac arrest.
You may be more likely to develop hyperkalemia while using these medications if you are elderly, dehydrated, have kidney disease, diabetes, or advanced heart failure. So, in view of the above, avoid taking Trimethoprim along with Lisinopril. Consult your treating doctor for an alternate effective but a safer antibiotic for the treatment of sinusitis.
Hope this answers your query. Let me know if I can assist you further.
Regards,
Dr. Mohammed Taher Ali
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