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What Does This Pathology Report Indicate?

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Posted on Tue, 3 Feb 2015
Question: What does this path report indicates. I hade a breast biopsy done, which shows Tumor characterized by pale myxoid stroma supporting multiple ductules arranged in a lobular architecture. Larger ducts area compressed branching and slitlike, There is no ductal hyperplasia or atypia. Adjacent breast tissue is composed of fibrous stroma supporting inactive lobules. I will be having the lump removed in a couple of weeks. It had grown 0.4mm in a month. The lump was found last year by MRI, mammogram does not pick it up.
doctor
Answered by Dr. T Chandrakant (1 hour later)
Brief Answer:
Looks to be benign as per the report you have posted above

Detailed Answer:
Hi.
Thanks for your query and nice to see you again.

The Pathology Reports posted by you suggests the following:
Tumor shows Myxoid stroma, means like mucus and can occur in any tumor. It is pale in this case.
This is supporting many ductules (smaller ducts) arranged in lobular (type of an arrangement) architecture (the way it is arranged).
Due to the stromal pressure the larger ducts appear as slits, and compressed branching.
There is NO Ductal ( of the ducts) Hyperplasia (increase in size) or ATYPIA (atypical meaning not abnormal)= All the ducts are typical means normal.
Adjacent (nearby) breast tissue has fibrous stroma supporting Inactive lobules (not lactating= not breast feeding for 5 years as you had mentioned).

This is indicative of a BENIGN (not cancerous) lesion.
It is a great decision to have the lump removed so that a formal biopsy report helps you the most.

How can one say it has grown 0.4 mm in a month - Is it by MRI readings ?

I hope this answers your query, as I have tried in as simple way as possible without a technical jargon

I would have loved to see the complete scanned copy of the report. You can attach with this question. Try to post one.


Above answer was peer-reviewed by : Dr. Chakravarthy Mazumdar
doctor
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Follow up: Dr. T Chandrakant (18 minutes later)
I am a RN so medical jargon is fine. I had an US in Nov then in Dec because of the MRI report wanted a closer look at the lump. I know the surgeon was unable to palpate the lump and said will have to use radioactive seed to locate it. She told me that she is not concerned about the lymph node size since it is morphological normal on US even though the cortical thickness is 3mm. She does not believe bx is warranted and is not concerned about the nipple secretion. She states that MRI and Mammogram did not show anything, even though I have extremely dense breast. She states they could removed the duct but she is not worried about it. I asked her could it be an papilloma. She states that it would have showed up on the imaging. I told her we can watch it over the next 3 months to make sure the lymph node has gone down and the discharge has stopped.
doctor
Answered by Dr. T Chandrakant (16 minutes later)
Brief Answer:
Wait and Watch is the best policy...

Detailed Answer:
Nice to know that you are a RN.
Noted the history an opinion of your Surgeon and your thoughts.

We have to believe what your Surgeon says as there is no palpable lump, morphologically normal lymph nodes on US, MRI and Mammography did not show anything, papilloma would have been detected on imaging,, that the duct can be removed but not bothered at the moment; that the duct could be removed but not bothered about the discharge.

Wait and Watch is the best policy at the moment, yet to be on regular examination.
This is the good policy you have accepted.

Above answer was peer-reviewed by : Dr. Chakravarthy Mazumdar
doctor
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Follow up: Dr. T Chandrakant (37 minutes later)
The lump is there she is not able to palpate it. The US shows the lump. The lump is in a different breast from the discharge and lymph node. So, myxoid stroma is not a concern.
doctor
Answered by Dr. T Chandrakant (7 hours later)
Brief Answer:
Not a concern

Detailed Answer:
Myxoid stroma is not a concern.

If you and / or your Surgeon is in doubt, taking a second opinion of another Surgeon is a better choice.

Note: For further inquiries on surgery procedure and its risks or complications book an appointment now

Above answer was peer-reviewed by : Dr. Chakravarthy Mazumdar
doctor
Answered by
Dr.
Dr. T Chandrakant

General Surgeon

Practicing since :1984

Answered : 19777 Questions

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What Does This Pathology Report Indicate?

Brief Answer: Looks to be benign as per the report you have posted above Detailed Answer: Hi. Thanks for your query and nice to see you again. The Pathology Reports posted by you suggests the following: Tumor shows Myxoid stroma, means like mucus and can occur in any tumor. It is pale in this case. This is supporting many ductules (smaller ducts) arranged in lobular (type of an arrangement) architecture (the way it is arranged). Due to the stromal pressure the larger ducts appear as slits, and compressed branching. There is NO Ductal ( of the ducts) Hyperplasia (increase in size) or ATYPIA (atypical meaning not abnormal)= All the ducts are typical means normal. Adjacent (nearby) breast tissue has fibrous stroma supporting Inactive lobules (not lactating= not breast feeding for 5 years as you had mentioned). This is indicative of a BENIGN (not cancerous) lesion. It is a great decision to have the lump removed so that a formal biopsy report helps you the most. How can one say it has grown 0.4 mm in a month - Is it by MRI readings ? I hope this answers your query, as I have tried in as simple way as possible without a technical jargon I would have loved to see the complete scanned copy of the report. You can attach with this question. Try to post one.