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What Does This Bone Biopsy Report Indicate?

Posted on Wed, 25 Jan 2017

Question: Bone biopsy. What does paucicellular marrow fibrosis mean? Said no neoplasm seen, no blasts. Suspected osteomylitis vs chronic inflammation in 6 yr old. Wbc low..everything else normal.
With a paucicellular biopsy could they miss leukemia?

Answered by Dr. Deepak Sundriyal (26 minutes later)

Brief Answer:
Hello dear. It means cell deficient marrow

Detailed Answer:
Hello dear. I have gone through the details. So a paucicellular marrow means the marrow precursors cells are few in number and fibrosis is a sequele to some infection or unknown causes. A cancer cannot be missed after a marrow examination. So please do not worry.
Thanks and regards

Above answer was peer-reviewed by : Dr. Remy Koshy

Follow up: Dr. Deepak Sundriyal (6 hours later)

What could cause chronic bone inflammation with a pathological fx if it isn't cancer and possibly not osteomylitis with a low wbc ....

Answered by Dr. Deepak Sundriyal (30 minutes later)

Brief Answer:
Hello. Most common cause is infection

Detailed Answer:
Hello dear. The most common cause is still chronic osteomyelitis. Other include idiopathic (means cause not identified).
Thanks and regards

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Above answer was peer-reviewed by : Dr. Yogesh D