Get your Health question answered in 3 easy steps
A Doctor will be with you shortly
Ask a Doctor Now
170 Doctors are Online

What causes high ALT, high WBC and chronic fatigue?

User rating for this question
Very Good
Answered by

Internal Medicine Specialist
Practicing since : 1981
Answered : 824 Questions
What are possible diagnosis for high ALT, high WBC, chronic fatigue, joint pain, bloated abdomen?
Posted Sat, 9 Aug 2014 in Infections
Answered by Dr. Karen Steinberg 2 hours later
Brief Answer:
Liver disease

Detailed Answer:
Thank you for using Healthcare Magic. My first thought with an elevated ALT is some kind of chronic liver disease. Hepatitis B and C both cause chronic liver disease, which over years or even decades may progress to cirrhosis and liver failure. During much of that time, you may experience few or no symptoms. When the liver disease is advanced, you can have swelling of the abdomen, fatigue, and sometimes joint pain. Infections in general can cause an elevated WBC count and fatigue. There is another condition called autoimmune hepatitis which can cause similar symptoms, especially joint pain. Autoimmune diseases may be associated with an elevated WBC.

If you were my patient, I would start with a careful physical exam, especially of your abdomen and liver. If there is evidence of fluid in your abdomen, that requires further evaluation to diagnose the cause. This may consist of an ultrasound and even removal of some of the fluid with a needle. Fluid would indicate advanced liver disease requiring prompt treatment. Assuming the bloodwork you've already had was part of a routine checkup, I would also add specific blood tests for hepatitis A, B, and C, and tests looking for autoimmune conditions that could be causing joint pain and injuring your liver. Chronic hepatitis B and C are both treatable. Hepatitis A can occur acutely with such symptoms, but generally resolves on its own and does not become chronic.

Check back with your doctor and see about getting the tests mentioned above. I am especially concerned about the bloated abdomen and would want to be sure it's not due to fluid.

Hope this answers your query. If you have further questions, I would be happy to answer them.

Above answer was peer-reviewed by
Share on Facebook
Share on Twitter
Share on Google+

The user accepted the expert's answer

Ask an Internal Med Specialist

© Ebix, Inc. All Rights Reserved.
All the information, content and live chat provided on the site is intended to be for informational purposes only, and not a substitute for professional or medical advice. You should always speak with your doctor before you follow anything that you read on this website. Any health question asked on this site will be visible to the people who browse this site. Hence, the user assumes the responsibility not to divulge any personally identifiable information in the question. Use of this site is subject to our Terms & Conditions
Already Rated.
Your rating:

Ask a Doctor