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What Causes Excessive Facial Hair And Cystic Acne While Testosterone Level Is 8?

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Posted on Wed, 21 Oct 2015
Question: Hi, I recently asked on this site about PCOS and received great advice however, I have another question. How can I have symptoms of too much testosterone (hair on face, cystic acne on chin and jawline) but when I received my lab results, my testosterone level is an 8. I just turned 40 and have been trying to do a fitness competition but I'm also struggling to put on muscle mass and holding on to a little fat. Please help explain....
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Answered by Dr. Binu Parameswaran Pillai (37 minutes later)
Brief Answer:
Spironolactone blocks actins of testosterone.

Detailed Answer:
Good day,

Noted your concern. In poly cystic ovary syndrome, your ovaries/adrenals may produce several male hormones like androstenedione, DHEA, DHEA-S etc apart from testosterone. It is not clear if you had got a Total testosterone level or a Free testosterone level done. Even if the total testosterone is normal, you may have elevated free testosterone which could cause several symptoms like acne and excessive hair growth.

Could you attach a copy of the investigations done ?
You are on Spironolactone which is an androgen receptor blocker ( testosterone receptor blocker). Testosterone is required for acquiring muscle mass. Since you are on an androgen recptor blocker like spironolactone which blocks the actions of testosterone, it may be difficut to develop a good muscle mass despite doing exercise. Please feel free to ask further if yiu need more clarifications.
Regards
Binu
Note: For more information on hormonal imbalance symptoms or unmanaged diabetes with other comorbid conditions, get back to us & Consult with an Endocrinologist. Click here to book an appointment.

Above answer was peer-reviewed by : Dr. Chakravarthy Mazumdar
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Answered by
Dr.
Dr. Binu Parameswaran Pillai

Endocrinologist

Practicing since :2003

Answered : 1439 Questions

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What Causes Excessive Facial Hair And Cystic Acne While Testosterone Level Is 8?

Brief Answer: Spironolactone blocks actins of testosterone. Detailed Answer: Good day, Noted your concern. In poly cystic ovary syndrome, your ovaries/adrenals may produce several male hormones like androstenedione, DHEA, DHEA-S etc apart from testosterone. It is not clear if you had got a Total testosterone level or a Free testosterone level done. Even if the total testosterone is normal, you may have elevated free testosterone which could cause several symptoms like acne and excessive hair growth. Could you attach a copy of the investigations done ? You are on Spironolactone which is an androgen receptor blocker ( testosterone receptor blocker). Testosterone is required for acquiring muscle mass. Since you are on an androgen recptor blocker like spironolactone which blocks the actions of testosterone, it may be difficut to develop a good muscle mass despite doing exercise. Please feel free to ask further if yiu need more clarifications. Regards Binu