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What Causes Elevated D-dimer Levels While Having Gallstones And Pressure In The Gallbladder Region?

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Posted on Thu, 15 Jun 2023
Question: D-Dimer came back 4.37. Tested yesterday for clots - negative. What else can ccontribute to high result? I am having pressure in gall bladder area. Have been told lots of gall stones. I have avoided surgery.
Had bilateral breast cancer lumpectomies last April. Any comments please.
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Answered by Dr. Michelle Gibson James (2 hours later)
Brief Answer:
Different possible causes...

Detailed Answer:

Hi,

D dimer is the breakdown product of fibrin which is part of the blood that plays a role in clotting and inflammation/irritation.

It can be elevated due to different conditions including a clot.

The other causes of elevated d dimer include-
(1) trauma
(2) inflammation, e.g. from infection
(3) liver disease
(4) heart disease
(5) malignancy is a rare cause
(6) high triglycerides (measured when looking at cholesterol)

It is possible that the increase is not due to a clot or another serious cause but may be related to slight trauma or infection.

If a clot is definitely ruled out by the other tests then further tests may be done to find the other cause.

Hope I have answered your query.

Regards,
Dr. Michelle Gibson James, General & Family Physician
Note: Consult a Urologist online for consultation about prostate and bladder problems, sexual dysfunction, kidney stones, prostate enlargement, urinary incontinence, impotence and erectile dysfunction - Click here.

Above answer was peer-reviewed by : Dr. Chakravarthy Mazumdar
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Answered by
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Dr. Michelle Gibson James

General & Family Physician

Practicing since :2001

Answered : 16808 Questions

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What Causes Elevated D-dimer Levels While Having Gallstones And Pressure In The Gallbladder Region?

Brief Answer: Different possible causes... Detailed Answer: Hi, D dimer is the breakdown product of fibrin which is part of the blood that plays a role in clotting and inflammation/irritation. It can be elevated due to different conditions including a clot. The other causes of elevated d dimer include- (1) trauma (2) inflammation, e.g. from infection (3) liver disease (4) heart disease (5) malignancy is a rare cause (6) high triglycerides (measured when looking at cholesterol) It is possible that the increase is not due to a clot or another serious cause but may be related to slight trauma or infection. If a clot is definitely ruled out by the other tests then further tests may be done to find the other cause. Hope I have answered your query. Regards, Dr. Michelle Gibson James, General & Family Physician