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What Can Be Done When Diagnosed With TP53, EGFR Mutation Metastasized To The Bones, Brain And Other Parts?

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Posted on Tue, 1 Oct 2019
Question: Hi,
My 44 year old brother lives in China and has been diagnosed Lung cancer stage 4. It's not small-cell type.
TP53, EGFR Mutation, right now is taking Gefitinib 250 mg made in XXXXXXX . It has metastasized to bones, brain and other parts. The medicine sold in China is extremely high and even patients take them, it can only help about 2 years. Is there any doctor who'd like to help him? Thank you in advance!
doctor
Answered by Dr. Monish De (1 hour later)
Brief Answer:
Erlotinib is less costly and should be used when disease progresses

Detailed Answer:
Hi

Your brother is suffering from non small cell lung cancer stage 4.

Since it is EGFR mutation positive Gefitinib 250 mg is a right choice of meditation for treatment

Though it is costly in china treatment with this drug will prolong his life for 2 years.

When the disease progresses with gefitinib he can take another drug called erlotinib which will prolong his life for 1 more year and is less costly

Regards

Dr Monish De

Oncologist


Above answer was peer-reviewed by : Dr. Yogesh D
doctor
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Follow up: Dr. Monish De (2 hours later)
Hi Dr. Monish De,
Thank you so much for your answer. Right now my brother is also taking radiotherapy. At this point , do you think it's necessary?
doctor
Answered by Dr. Monish De (14 hours later)
Brief Answer:
Radiotherapy is needed

Detailed Answer:
Hi

Since your brothers lung cancer has spread to bones and brain radiotherapy is also needed to reduce the symptoms of bone pain, nausea and vomiting which may occur due to spread of the lung cancer to bones, brain and other parts.

Radiotherapy also halts further spread of lung cancer

Regards

Dr Monish De

Oncologist
Note: For further queries related to kidney problems Click here.

Above answer was peer-reviewed by : Dr. Prasad
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Answered by
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Dr. Monish De

Oncologist

Practicing since :2004

Answered : 2229 Questions

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What Can Be Done When Diagnosed With TP53, EGFR Mutation Metastasized To The Bones, Brain And Other Parts?

Brief Answer: Erlotinib is less costly and should be used when disease progresses Detailed Answer: Hi Your brother is suffering from non small cell lung cancer stage 4. Since it is EGFR mutation positive Gefitinib 250 mg is a right choice of meditation for treatment Though it is costly in china treatment with this drug will prolong his life for 2 years. When the disease progresses with gefitinib he can take another drug called erlotinib which will prolong his life for 1 more year and is less costly Regards Dr Monish De Oncologist