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Weaning Off Venlafaxine, Have Stomach Discomfort, Crying A Lot For No Reason. Appreciate Some Advice

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Posted on Thu, 11 Oct 2012
Question: i am currently weaning off venlafaxine slowely this is second week i am experiencing sickness uncomfortable stomach and and anxious stomach as well. not to far left to go maybe and two weeks but will this continue i can honestly say this has been the worse drug i have ever been on also i am crying alot for no reason would appreciate some advice.
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Answered by Dr. Susanta Padhy (2 hours later)
Hello xxxxxx

Thanks for the query

I must salute you for having patience and motivation for treatment of OCD of 30 years duration

OCD usually responds better to clomipramine then Venlafexine.

If Venlafexine is discontinued rapidly it can result in the symptoms that you are going through now.

To avoid such venlafexine discontinuation symptoms, the dose reduction should be 10-25 % per week. But the rate of dose decrease can vary sometimes.

Invariably, such discontinuation symptoms should not continue for more than few weeks to a maximum of a couple of months.

Treatment of such symptoms is to decrease the rate of tapering of dose and duration, plus, take some anxiolytics for a short period. This would need you to see your physician so that the dose can be reduced more gradually than it is being done. In addition, a prescription of anxiolytics would also be required.

I sincerely wish you a speedy recovery


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Above answer was peer-reviewed by : Dr. Aparna Kohli
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Answered by
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Dr. Susanta Padhy

Psychiatrist

Practicing since :1998

Answered : 415 Questions

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Weaning Off Venlafaxine, Have Stomach Discomfort, Crying A Lot For No Reason. Appreciate Some Advice

Hello xxxxxx

Thanks for the query

I must salute you for having patience and motivation for treatment of OCD of 30 years duration

OCD usually responds better to clomipramine then Venlafexine.

If Venlafexine is discontinued rapidly it can result in the symptoms that you are going through now.

To avoid such venlafexine discontinuation symptoms, the dose reduction should be 10-25 % per week. But the rate of dose decrease can vary sometimes.

Invariably, such discontinuation symptoms should not continue for more than few weeks to a maximum of a couple of months.

Treatment of such symptoms is to decrease the rate of tapering of dose and duration, plus, take some anxiolytics for a short period. This would need you to see your physician so that the dose can be reduced more gradually than it is being done. In addition, a prescription of anxiolytics would also be required.

I sincerely wish you a speedy recovery