Get your Health question answered in 3 easy steps
A Doctor will be with you shortly
Ask a Doctor Now
182 Doctors are Online

Test showed low immunoglobulin m. What does this mean? Any complication?

User rating for this question
Answered by

General & Family Physician
Practicing since : 2002
Answered : 106 Questions
Dear Doctor,
Please guide for following results-
Immunnoglobin M =0.36g/L, Im G 12.04 g/L, C4 = 0.43 G/L, C3= 1.29 G/l,
Na= 141, K =4.6, CO2 =27, Urea 6.4, Beta 2 Globulin 5.28 /L, Gamma Globulin 11.9 g/L
Dear Doctor,
,Lab shows that Ig M are low like 50 % low, in urine dysmorphic red cells, ESR is always high, ANC 1:80,
What does is low IMMUGLOBIN M means ? does this serious, what tests can be done in order to evaluate further.
Posted Tue, 22 Jan 2013 in Blood Disorders
Answered by Dr. Mohammed Kappan 18 hours later

Thanks for the query.

IgM ( Immunuglobulin M) is one among the five types of immunoglobulin present in a person. Other types are IgG, Ig A, IgD and IgE. Immunoglobulin is a type of protein that helps in our immunity.

Usually the deficiency of IgM remains asymptomatic. Hence it is found out only when being investigated for other diseases like autoimmune diseases or malignancies. All these immunoglobulin are produced by B-lymphocytes in the body. When an IgM deficiency is noted, the first thing to do is to check whether other immunoglobulin are also reduced. If it is an isolated IgM deficiency, there is not much of scientific data to enlighten us with its causes or effects. With the investigation reports you have posted here, it does not look serious.

What other tests can be done for evaluation?
-     Serum immunoelectrophoresis to rule out clonal B cell disorders such as multiple myeloma, chronic lymphocytic leukemia etc.
-     Flow cytometry for B cells with surface IgM.
-     Routine investigations to rule out associated infections may be required.

Hope I have addressed all your concerns. Please use any answer clarification before closing and rating this answer. I will be happy to explain or expand on any issue you may have.

Thank you

Above answer was peer-reviewed by
Share on Facebook
Share on Twitter
Share on Google+
Question is related to
Diseases and Conditions

The user accepted the expert's answer

Ask a Hematologist

© Ebix, Inc. All Rights Reserved.
All the information, content and live chat provided on the site is intended to be for informational purposes only, and not a substitute for professional or medical advice. You should always speak with your doctor before you follow anything that you read on this website. Any health question asked on this site will be visible to the people who browse this site. Hence, the user assumes the responsibility not to divulge any personally identifiable information in the question. Use of this site is subject to our Terms & Conditions
Already Rated.
Your rating:

Ask a Doctor