Suggest an alternative medication in place of Fulvestrant with Palbociclib

Posted on Fri, 8 Mar 2019 in Cancer
Question: I’m trying to find out what can be done when palbociclib and fulvestrant have stopped working have been on it14 months

Answered by Dr. Monish De 24 minutes later
Brief Answer:
Tablet capecitabine recommended.

Detailed Answer:


Fulvestrant with palbociclib is used for metastatic breast cancer.

Since it has stopped working and you are on tamoxifen I would advise you to go for tablet capecitabine.

This drug has shown significant and consistent improvement in progression-free survival in breast cancer which has spread to other parts of the body.

Its side effects are severe nausea or vomiting, stomach pain or upset and loss of appetite which can be managed symptomatically.

You can consult your local doctor regarding it.

Hope I have answered your query.

Dr. Monish De, Oncologist
Above answer was peer-reviewed by : Dr. Nagamani Ng
Answered by
Dr. Monish De


Practicing since :2004

Answered : 2233 Questions


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