Tamoxifen

What is Tamoxifen?

Tamoxifen is an antagonist of the estrogen receptor in breast tissue via its active metabolite, hydroxytamoxifen. In other tissues such as the endometrium, it behaves as an agonist, and thus may be characterized as a mixed agonist/antagonist.

Questions and answers on "Tamoxifen"

Hi I have been on tamoxifen since Nov 2014 for sclerosis mesenteritis I have been postmenopausal for two years this XXXXXXX on May 2 I started bleeding and cramping saw NP did biopsy and transnational ultrasound showed 7mm endometrial and polyp had D and C hysterscope a week ago everything came back normal . Now wondering if this will happen again because of the tamoxifen

doctor1 MD

Brief Answer:
Tamoxifen might cause it again

Detailed Answer:
Hi,

Tamoxifen leads to endometrial hypertrophy. Hence you had this growth and polyp.

You guessed it right. This might happen again as you are on tamoxifen.

Let me know if you need any more information.

Regards,
Dr....

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Can the breast cancer drug Temoxafen also protect females from the low range HPV's ? as i have been reading they shut down that and hepes to a degree

doctor1 MD

Brief Answer:
Tamoxifen

Detailed Answer:
Hello and thank you for asking

Some studies have shown that tamoxifen can stimulate the proliferation of some of subtype of HPV.It is the peak of proliferation 2-4 hours after the tamoxifen use

After 24 hours of tamoxifen use the proliferation it's lower...

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What happens to me if I stop taking tamoxifen. I had 16 radiation treatments for stage 1 invasive dcis with clear lymph node. The meds blow my stomach up and put weight on my belly.

doctor1 MD

Brief Answer:
better you continue

Detailed Answer:
I do not know the full details.

However, the disease must be ER/PR positive and hence tamoxifen has been started. It has beneficial effects on the disease. Some side effects would be there.

It is recommended to continue. Please check with your...

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my daughter had a double mastectomy, 6 chemo treatments three weeks apart, then had her ovaries removed to stop hormone production all last year. With the ovaries gone, does she still need to take the tamoxifen citrate?

doctor1 MD

Brief Answer:
Hello. Yes, she requires Tamoxifen

Detailed Answer:
Hello dear.

I have gone through the details. So to stop the extra-ovarian source of estrogen from acting, Tamoxifen or another hormonal agent needs to be taken.

Let me know if I can assist you further.

Thanks and regards...

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Interaction between Tamoxifen and Essiac (trade name for 4-herb tea herbal healer therapy)?

doctor1 MD

Brief Answer:
Hi and welcome to HCM

Detailed Answer:
There is no evidence about bad interactions or side effects of Essiac and tamoxifen when taken together. There are reported side effects when some other herbal products are taken during tamoxifen therapy but essiac is not one of them. WIsh you...

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I have been taking tamoxifen oral for 5 years. Had to miss my oncologist appt this month and unable to get in until after the holidays. I ran out of prescription and stopped taking the medication last week as the doctor had said it was time to end the med after 5 years.
Can tamoxifen be stopped without side effects?

doctor1 MD

Brief Answer:
Hello dear. You should continue tamoxifen

Detailed Answer:
Hello dear. I have gone through the details.

So the latest data from attom and atlas trials advice to continue tamoxifen for a period of 8 to 10 years. You must continue again to decrease the risk of recurrence of cancer....

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It's been 11months after radical mastectomy surgery, isn't it late to start radiation if I'm takin tamoxifen?




doctor1 MD

Brief Answer:
Radiation therapy is generally started earlier. But can also start late. It

Detailed Answer:
hi and thanks for the query

radiation therapy can come after tamoxifen therapy. most of the time, when to start and the dosage or order of treatment options depend on your doctor's...

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Can I take garcinia cambogia while on tamoxifen?

doctor1 MD

Brief Answer:
side effect profile not known, seems safe

Detailed Answer:
Hello mam, thanks for trusting health care magic.
Garcinia is gaining a lot of popularity these days because of its role in weight loss.
But there are minimal studies related to the side effect profile of this drug....

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is it ok to take amoxicillin with tamoxifen & clomid, im just worried about interactions?

Kind Regards

doctor1 MD

Brief Answer:
Yes.

Detailed Answer:
Hello!

Thank you for the query.

Yes, you can take this medicines together. There is no interaction between Tamoxifen, Clomid and Amoxicillin. So you can take if safely.

Hope this will help. Feel free to ask further questions....

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Dear Doctor
Do I need a biopsy if I had some postmenstrual bleeding after stopping Tamoxifen which I took for 4 years due to breast cancer? I did ultrasounds and the result was that my ovaries are fine and also uterus and cervix are normal. The Endometrium measures 5mm in thickness is exactly the same it was in 2014 after my first postmenstrual bleeding. Not only, the last result on Sept. 30 - 2015 show that a little cyst I had in one of the ovaries has gone away, so the result is, in fact, even better then the previous ultrasound I did in January 2014. What are the risks of actually having endometrial cancer in my situation because I am reluctant to doing all these tests.
Thank you
XXXX

doctor1 MD

Brief Answer:
Everything is normal

Detailed Answer:
Hello Mrs Patrizia, thanks for trusting health care magic.
There is nothing to worry about as it is very common to have estrogen withdrawl bleeding after leaving tamoxifen.
Definitely there is increased risk of endometrial cancer after...

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Recent questions on  Tamoxifen

doctor1 MD

I had chemo 2 years ago Cytoxin/Taxotere for breast cancer and am currently on Tamoxifen, Toprol 100mg,TriamtereneHCTZ 37.25mg. I was taking Lortab 7.25-500mg but that was currently changed to Lortab 7.5-325mg. Last night was the first time taking the new pills, and I keep get this fluttering like heart thing that makes me want to breath really deep or cough then I m fine. Now you should know I extremely sensitive to meds as changing from one brand of tamoxifen to another is truly a beast!

doctor1 MD

I am 18 years old, 5 8 and weigh 155 lbs. I took a prohormone, which i am aware is stupid. its two compounds are 4-chloro-17a-methyl-androst-1, 4-dien3-17b-diol (superdrol) -15mg and 2a,17a dimethyl-etiocholan-3-one, 17b-ol (halodrol) -25mg. My post cycle therapy is tamoxifen citrate (nolvadex)- 20mg. My question is, is there any chance of me developing gynecomastia from this? and since the nolva is 20mg, is it okay to take one pill a day?

doctor1 MD

I have been on Tamoxifen for the past three years. I was off it for about a month due to an allergic reason. I notice a complete absence of joint pain. I am now on it again - made by Watson. The joint and muscle pains have returned. Am I imaging that Tamoxifen is the source?

doctor1 MD

I got a Skin Sparing Mastectomy done on my right breast on March 30th, 2011 as the tumour was malignant. Post that i completed my 8 cycles of Dose-Dense Chemotherapy followed by 28 fractions of radiation therapy. My ER & PR are 90% positive & hence now i am on hormone therapy taking 1x20mg tablet of "Tamoxifen" daily & will have to do so for the next 5 years. I have attached my post surgical report. My Onco yesterday also advised that i get Injection Zoladex for 2 years (@ 3.6 mg monthly or 10.8 mg quarterly). I am 36 years unmarried. I do understand that zoladex will suppress the function of the ovaries for 2 years. My ques:1)By how much does Zoladex reduce chances of recurrence when taken with tamoxifen in comparison to only Tamoxifen ? Basis my report is it advisable to get Zoladex shots ? and why is 2 years considered ideal & not less or more ?

doctor1 MD

Does tamoxofin have the side effect of weakening bones. I am 75 and took it for 6 years. email YYYY@YYYY .

doctor1 MD

Hi My mother age almost 48 Yrs and now she. is facing BP High issue her BP 100/160 she has recently 24 did fast ... she has taking tamoxifen tab and as per oncologist for that tab not an issue ...can you help me here is last doctor visit...

doctor1 MD

Hi My mother age 48 and she is taking tamoxifen tab 20 daily basis ... currently she is facing BP High problem and Her BP is 100/150 here is last doctor visit precrtion is attached..Kindly suggest on the same

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