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Is Cefixome And Zithromax Effective In Treatment Of Gonorrea?

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Posted on Tue, 27 May 2014
Question: I was wondering the success rate of cefixome and zithromax against gonorrea. I know the injection is more recomended.
doctor
Answered by Dr. Dr. Kakkar (22 minutes later)
Brief Answer:
Treatment of gonorrhea

Detailed Answer:
Hello and welcome to healthcaremagic

I am Dr. Kakkar. I have gone through your concern and I have understood it

Treatment options for Gonorrhea are:

--Single I/M injection of Ceftriaxone 250 mg is recommended by CDC. It has >99% success rate for uncomplicated urogenital and anorectal gonorrhea and 99% success rate for pharayngeal gonorrhea. This regime is preferred because it provides sustained, high bactericidal levels in the blood.

--However, single dose of Cefixime 400mg along with single dose of Azithromycin 1gm is also recommended by CDC. It has the advantage of oral administration over ceftriaxone. While cefixime acts against Gonococcus, Azithromycin is given for Non-Gonococcal urethritis (due to chlamydia, mycoplasma etc), which is frequently co-existent. This regime has 97.5% success rate for uncomplicated urogenital and anorectal gonorrhea. Cefixime has limited efficacy against pharyngeal gonorrhea.

regards
Above answer was peer-reviewed by : Dr. Chakravarthy Mazumdar
doctor
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Follow up: Dr. Dr. Kakkar (1 hour later)
Thank you very much for your answer. When you say uncomplicated does that mean the straid or the symptoms? I am having a very small white discahrge in the morning, and I have to "force" it out no other symptoms..
doctor
Answered by Dr. Dr. Kakkar (42 minutes later)
Brief Answer:
Gonorrhea treatment

Detailed Answer:
Hi.

Gonorrhea can be associated with complications which might require hospitalization:

Delay in treatment or inadequate treatment or low immunity(HIV coinfection) might favour these complications

--Epididymitis and/or orchitis.
--Prostatitis.
--Systemic dissemination of gonorrhoea, e.g conjunctivitis, skin lesions(disseminated gonococcal Infections).
--Reactive arthritis.
--Pelvic inflammatory disease (PID) in females.

Gonorrhea limited to urethra is uncomplicated, as in your case.

regards
Above answer was peer-reviewed by : Dr. Vaishalee Punj
doctor
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Follow up: Dr. Dr. Kakkar (2 hours later)
I see thank you very much. One last question would i Take the cefixime 400mg and the zithromax 1g all at once?
doctor
Answered by Dr. Dr. Kakkar (1 minute later)
Brief Answer:
Gonorrhea treatment

Detailed Answer:
Hi.

Yes, all at once.

regards
Note: Consult a Sexual Diseases Specialist online for further follow up- Click here.

Above answer was peer-reviewed by : Dr. Yogesh D
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Answered by
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Dr. Dr. Kakkar

Dermatologist

Practicing since :2002

Answered : 9612 Questions

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Is Cefixome And Zithromax Effective In Treatment Of Gonorrea?

Brief Answer: Treatment of gonorrhea Detailed Answer: Hello and welcome to healthcaremagic I am Dr. Kakkar. I have gone through your concern and I have understood it Treatment options for Gonorrhea are: --Single I/M injection of Ceftriaxone 250 mg is recommended by CDC. It has >99% success rate for uncomplicated urogenital and anorectal gonorrhea and 99% success rate for pharayngeal gonorrhea. This regime is preferred because it provides sustained, high bactericidal levels in the blood. --However, single dose of Cefixime 400mg along with single dose of Azithromycin 1gm is also recommended by CDC. It has the advantage of oral administration over ceftriaxone. While cefixime acts against Gonococcus, Azithromycin is given for Non-Gonococcal urethritis (due to chlamydia, mycoplasma etc), which is frequently co-existent. This regime has 97.5% success rate for uncomplicated urogenital and anorectal gonorrhea. Cefixime has limited efficacy against pharyngeal gonorrhea. regards