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I Was Recently Prescribed One Dose Of Azithromycin For Mycoplasma

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Posted on Sat, 12 Oct 2019
Question: I was recently prescribed one dose of Azithromycin for mycoplasma Genitalium, how long should I wait after taking the medication before getting tested again
doctor
Answered by Dr. Sankaranantham Murugan (2 hours later)
Brief Answer:
Urine examination for the presence of pus cells is enough.

Detailed Answer:
Hi,
Welcome to 'Ask A Doctor' service.
Thanks for posting your query.

Genital Mycoplasma infection is usually diagnosed by ruling out the common causes of genital infections like Gonorrhea, Chlamydia, and Trichomonas.

Test for cure usually not required. Taking the drugs for 2 weeks and the relief of symptoms will assure that you are free from Mycoplasma genitalium infection. Urine deposits examined for the presence of pus cells will help in most cases. If it remains less than 4 pus cells, it assures that you had been cured.

Moreover it depends upon what type of test was used to diagnose the Mycoplasma infection. If it is through isolation of organism, then repeat culture will show no growth after the treatment.
If it is through serological test then depend upon whether it is a antibody detection test (IgG) it will be persisting even after treatment.

If it is through PCR or NAAT it will take not less than few months to show a negative test.
If you want more information, a microbiologist is the ideal person to clear your doubts in this regards.

Dr S.Murugan


Above answer was peer-reviewed by : Dr. Arnab Banerjee
doctor
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Follow up: Dr. Sankaranantham Murugan (40 hours later)
The test was done with a PCR test. So even after treatment and relief of symptoms I could still test positive on a PCR test for a few month? Does that mean I could still infect others even if the infection symptoms have cleared
doctor
Answered by Dr. Sankaranantham Murugan (11 minutes later)
Brief Answer:
You are free from infection after treatment. No further transmission possible

Detailed Answer:
Hi,
Welcome back.

Only antibody tests remain positive for a few months after treatment and in some infections remain forever... Permanent immunity. Not with PCR tests.

Even if the antibody tests remain positive after adequate treatment, organisms would be eliminated, but immunity will be present. That doesn't mean that you need further treatment or you will infect others. You are absolutely free from infection after treatment.

Reinfection can occur if your partner hadn't been treated if she already infected.

Dr. S Murugan



Above answer was peer-reviewed by : Dr. Arnab Banerjee
doctor
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Follow up: Dr. Sankaranantham Murugan (42 minutes later)
So a PCR test after treatment can assure me I am clear
Of the infection. How long after the initial treatment does should I test again
doctor
Answered by Dr. Sankaranantham Murugan (6 hours later)
Brief Answer:
A microbiologist is the competent person to answer your question.

Detailed Answer:
Hi,
Welcome back.
I had much experience with HIV PCR results and follow up. The course of HIV is entirely different from that of Mycoplasma Genitalium which is a bacterial diseases and amenable to antibiotics. I don't have any experience with mycoplasma PCR.
So it will be better for you to clarify the same from a microbiologist about when to repeat the test after the treatment in case of Mycoplasma Genitalium infection.
Dt S.Murugan
Note: Consult a Sexual Diseases Specialist online for further follow up- Click here.

Above answer was peer-reviewed by : Dr. Raju A.T
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Answered by
Dr.
Dr. Sankaranantham Murugan

HIV AIDS Specialist

Practicing since :1974

Answered : 3110 Questions

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I Was Recently Prescribed One Dose Of Azithromycin For Mycoplasma

Brief Answer: Urine examination for the presence of pus cells is enough. Detailed Answer: Hi, Welcome to 'Ask A Doctor' service. Thanks for posting your query. Genital Mycoplasma infection is usually diagnosed by ruling out the common causes of genital infections like Gonorrhea, Chlamydia, and Trichomonas. Test for cure usually not required. Taking the drugs for 2 weeks and the relief of symptoms will assure that you are free from Mycoplasma genitalium infection. Urine deposits examined for the presence of pus cells will help in most cases. If it remains less than 4 pus cells, it assures that you had been cured. Moreover it depends upon what type of test was used to diagnose the Mycoplasma infection. If it is through isolation of organism, then repeat culture will show no growth after the treatment. If it is through serological test then depend upon whether it is a antibody detection test (IgG) it will be persisting even after treatment. If it is through PCR or NAAT it will take not less than few months to show a negative test. If you want more information, a microbiologist is the ideal person to clear your doubts in this regards. Dr S.Murugan