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I Need A Nephrologist To Answer This Question. My 58

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Posted on Wed, 10 Apr 2019
Question: I need a Nephrologist to answer this question. My 58 year old husband was just dx with possibly having a TIA while on vacation. The MRI showed no sign of stroke. The ER dr told him to take one aspirin / day and follow up with his Nephrologist when he returned home. My husband's Nephrologist has retired and the one who took his place is not responding to our calls.

My husband had PKD and received a kidney 14 years ago. What are the drawbacks of taking blood thinners after a kidney transplant? Does one exist that KT patients can take?
doctor
Answered by Dr. Dr. Ivan Romich (43 hours later)
Brief Answer:
no known drawbacks for aspirin

Detailed Answer:
Hi and welcome.
There are no data which suggest that blood thinners are contraindicated in KT patients. KT patients regularly take warfarin, Pradaxa,Clopidogrel or Aspirin. For Aspirin, there are no proofs that these medications affect kidney function significantly. Newer anticoagulants such as NOAC, dabigatran or eliquis are safe as well but its dosage should be controlled and checked regularly. Warfarin may be more problematic and if this is recommended than consultation with hematologist is required. SO at this point, i think that aspirin should be continued as recommended since benefit is much higher than possible side effects. Complete neurologic work up is required, including carotid artery ultrasound, heart ultrasound and brain MRI since it will help to find the exact cause of TIA which may be a thrombotic plaque in heart or large blood vessels.

If you have further questions, feel free to ask. Wish you good health. Regards
Above answer was peer-reviewed by : Dr. Prasad
doctor
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Follow up: Dr. Dr. Ivan Romich (2 hours later)
Thsnk you. My husband was told 14 years ago when he received his kidney to avoid taking aspirin as it could interfere and cause rejection. Maybe they have found out since then that it doesn’t have the adverse effects they once thought.

He will be seeing the team at Mayo Clinic next Thursday. Thanks again
doctor
Answered by Dr. Dr. Ivan Romich (22 minutes later)
Brief Answer:
There is no evidence for the negative impact of aspirin

Detailed Answer:
Hi,

It may have been the case in the past but relevant studies even show that administration of aspirin in kidney transplant recipients is associated with reduced risks of allograft failure.

Of course, when KT patients are taking any new medicine, it should be discussed with the nephrologist, but I don't think that aspirin is problematic.

Regards

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Above answer was peer-reviewed by : Dr. Arnab Banerjee
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Answered by
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Dr. Dr. Ivan Romich

General Surgeon

Practicing since :2008

Answered : 13886 Questions

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I Need A Nephrologist To Answer This Question. My 58

Brief Answer: no known drawbacks for aspirin Detailed Answer: Hi and welcome. There are no data which suggest that blood thinners are contraindicated in KT patients. KT patients regularly take warfarin, Pradaxa,Clopidogrel or Aspirin. For Aspirin, there are no proofs that these medications affect kidney function significantly. Newer anticoagulants such as NOAC, dabigatran or eliquis are safe as well but its dosage should be controlled and checked regularly. Warfarin may be more problematic and if this is recommended than consultation with hematologist is required. SO at this point, i think that aspirin should be continued as recommended since benefit is much higher than possible side effects. Complete neurologic work up is required, including carotid artery ultrasound, heart ultrasound and brain MRI since it will help to find the exact cause of TIA which may be a thrombotic plaque in heart or large blood vessels. If you have further questions, feel free to ask. Wish you good health. Regards