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Exforge Has Previously Been Taken But Has Had More Side Effects. The Thyroid Levels Are Slightly High And Have Been Told That The Thyroid Could Be Under Active. Could This Lead To Higher Blood Pressure?

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Posted on Wed, 22 Mar 2023
Question: Hi,
I have a friend with high blood pressure. She has taken Tritace 5mg recently and it has brought down the systolic figure but the diastolic remains above 95. The pulse is a little high at about 85 bpm. What could this point towards?

Are there any medications apart from Tritace that could reduce the diastolic figure and can Tritace be taken safely long term? Exforge has previously been taken but has had more side effects. The thyroid levels are slightly high and have been told that the thyroid could be under active. Could this lead to higher blood pressure?


Thanks,
Regards.
doctor
Answered by Dr. Ilir Sharka (18 minutes later)
Brief Answer:
I would recommend as follows:

Detailed Answer:
Hello,

Regarding your concern, I would explain that as her diastolic blood pressure values remain high, this indicates uncontrolled diastolic hypertension, which is a type of arterial hypertension, leading to an increased cardiovascular risk.

This means that Tritace is not very effective in controlling her blood pressure values. This is a safe drug for long term treatment of arterial hypertension, if she tolerates it well.

From the other hand, you should know that uncontrolled high blood pressure values, coupled with a high heart rate could be related to thyroid gland dysfunction.

For this reason, before making any further changes to her therapy, I would recommend consulting first with an endocrinologist and discussing about the best treatment option in order to stabilize her thyroid gland function.

If her high diastolic blood pressure values persist, despite the normalization of thyroid hormone levels, I would recommend adding a calcium channel blocker (lercanidipine or amlodipine) to help lower diastolic blood pressure values.

She should discuss with her doctor on the above issues.

I remain at your disposal for any further questions whenever you need!

Hope to have been helpful!

Wishing good health,

Dr. Iliri
Above answer was peer-reviewed by : Dr. Chakravarthy Mazumdar
doctor
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Follow up: Dr. Ilir Sharka (36 hours later)
Thankyou Dr. Iliri,

I have seen the GP and according to him, the underactive thyroid and high TSH readings could not result in high blood pressure but the overactive thyroid might do so, would you agree or is this incorrect?

Would all calcium channel blocking drugs be effective at treating high diastolic pressures? Are there potentially any other drugs that are better than Tritace at managing high diastolic blood pressure?


Thankyou,
Regards.
doctor
Answered by Dr. Ilir Sharka (4 hours later)
Brief Answer:
My opinion as follows:

Detailed Answer:
Hello again!

Regarding your concern, you should know that hypothyroidism can lead to high blood pressure too, as well as hyperthyroidism. It is explained with the increased peripheral resistance.

For this reason, the normalization of thyroid hormone levels may improve blood pressure values too.

Regarding calcium channel blockers, they are better compared to Tritace for diastolic hypertension. She can choose any of them (amlodipine, lercanidipine, etc), but the choice is usually based on individual tolerance (for ex.: lercanidipine may have less adverse effects like leg swelling compared to amlodipine,etc.. ).

You should discuss with her doctor on the above issues.

Hope to have been helpful!

Kind regards,

Dr. Iliri
Above answer was peer-reviewed by : Dr. Chakravarthy Mazumdar
doctor
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Follow up: Dr. Ilir Sharka (29 hours later)
Thankyou Dr. Iliri,

The GP did prescribe a kidney ultrasound. Would this be linked to the thyroid or what type of defects in the kidney are possibly linked to the high blood pressure. Are they possibly structural issues?



Thankyou,
Regards,
Pierre
doctor
Answered by Dr. Ilir Sharka (15 hours later)
Brief Answer:
I would explain as follows:

Detailed Answer:
Dear XXXXXXX

All chronic kidney disorders, which lead to chrnic structural changes in the kidneys, can lead to uncontrolled high blood pressure.

From the other hand, narrowing of the renal arteries is another cause of arterial hypertension.

Kidney ultrasound can help detect the structural changes and also examine the blood flow in the renal arteries.

This test is not related to the thyroid dysfunction, but is another tests which can help investigate for kidney disorders underlying uncontrolled high blood pressure.

Hope to have clarified some of your uncertainties!

Wishing all the best,

Dr.Iliri
Note: For further queries related to coronary artery disease and prevention, click here.

Above answer was peer-reviewed by : Dr. Vaishalee Punj
doctor
Answered by
Dr.
Dr. Ilir Sharka

Cardiologist

Practicing since :2001

Answered : 9536 Questions

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Exforge Has Previously Been Taken But Has Had More Side Effects. The Thyroid Levels Are Slightly High And Have Been Told That The Thyroid Could Be Under Active. Could This Lead To Higher Blood Pressure?

Brief Answer: I would recommend as follows: Detailed Answer: Hello, Regarding your concern, I would explain that as her diastolic blood pressure values remain high, this indicates uncontrolled diastolic hypertension, which is a type of arterial hypertension, leading to an increased cardiovascular risk. This means that Tritace is not very effective in controlling her blood pressure values. This is a safe drug for long term treatment of arterial hypertension, if she tolerates it well. From the other hand, you should know that uncontrolled high blood pressure values, coupled with a high heart rate could be related to thyroid gland dysfunction. For this reason, before making any further changes to her therapy, I would recommend consulting first with an endocrinologist and discussing about the best treatment option in order to stabilize her thyroid gland function. If her high diastolic blood pressure values persist, despite the normalization of thyroid hormone levels, I would recommend adding a calcium channel blocker (lercanidipine or amlodipine) to help lower diastolic blood pressure values. She should discuss with her doctor on the above issues. I remain at your disposal for any further questions whenever you need! Hope to have been helpful! Wishing good health, Dr. Iliri