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Can Proton Pump Inhibitors Cause Bone Loss?

Posted on Mon, 23 Jan 2017

Question: I am looking for the page where I can list my medications . I am on Nexium and wish to know how to replace those nutrients lost by taking this PPI

Answered by Dr. Dr. Muhammad Sareer Khalil (1 hour later)

Brief Answer:
Explained

Detailed Answer:
Hello and Welcome

I appreciate your concern

With long term PPI use , osteoporosis has been reported so the only supplement you would require would be vitamin D and calcium supplementation.

The evidence for other nutrient losses is not substantial.

Wishing you best of health

Thanks

Let me know if you have any query

Please consult your doctor before deciding on any further course of action.

For future follow up / correspondence you may ask me directly at the link given below

http://doctor.healthcaremagic.com/Funnel?page=askDoctorDirectly&docId=68107

Dr. M.S. Khalil

Above answer was peer-reviewed by : Dr. Chakravarthy Mazumdar

Follow up: Dr. Dr. Muhammad Sareer Khalil (28 minutes later)

My follow up question has to do with every report, research paper and warnings from my FMD and others on Nexium. Apparently it causes many nutrients NOT to be absorbed, such as Zinc, Iron, etc. Also I have read that it is vital in the absorbtion, or lack thereof, of Vit B12 which causes MANY problems. I have osteoporosis and am on Vit D and Prolia. I am still losing nutrients and have become more anemic and have many other problems. So, it is not a benign situation as has been implied.

Answered by Dr. Dr. Muhammad Sareer Khalil (9 hours later)

Brief Answer:
Explained

Detailed Answer:
Hello again.

Firstly, nutrient loss per say doesn't cause anemia. Anemia is either due to iron, b 12 or folate deficiency and clearly shows up on peripheral smear of the blood. It can be corrected in a targeted manner if required.

If you are concerned about nutrient loss then, a good strategy would be to check the levels of these minerals and supplement them accordingly instead of pumping in every mineral without knowing which deficiency is there in the first place.

Wishing you best of health

Thanks

Note: For more detailed guidance, please consult an Internal Medicine Specialist, with your latest reports. Click here..

Above answer was peer-reviewed by : Dr. Chakravarthy Mazumdar