HealthCareMagic is now Ask A Doctor - 24x7 | https://www.askadoctor24x7.com

question-icon

Can Larsen Syndrome Cause Any Complications In Future Pregnancies?

default
Posted on Mon, 2 Feb 2015
Question: I'am diagnosed with Larsen Syndrome, i was born with a club foot and had a surgery to fix my foot. I'm 130cm tall and i got a premature arthritis in my knees.
My question is will i face difficulties getting or being pregnant?
Will my kids be defected by the gene? like getting joint dislocation or have short figure?

doctor
Answered by Dr. Vjollce Mbiarra (42 minutes later)
Brief Answer:
There is no problem getting or being pregnant

Detailed Answer:
Hi dear and thanks for your query.
I understand your concern and I will try to help you.
Larsen syndrome is a rare syndrome that have relation especially with Bones(bones dislocation)
Women with this syndrome have no problem getting or being pregnant but Keeping pregnancy for 9 months may be difficult.
Another problem for women with Larsen syndrome is that this syndrome can be transmitted in children and this vary, what type of defect do you have, is recesive or dominant.
As per your symptoms, it may be recesive.
Hence you are free to be pregnant and consult with an geneticist to calculate chances that you have to transmit Larsen syndrome in your future children.
Feel free to discuss any other questions.

All the best



Above answer was peer-reviewed by : Dr. Vinay Bhardwaj
doctor
default
Follow up: Dr. Vjollce Mbiarra (49 minutes later)
hi,

What's the difference between recessive and dominant?
Do you know any geneticists to consult about this ?
doctor
Answered by Dr. Vjollce Mbiarra (37 minutes later)
Brief Answer:
there is a big difference

Detailed Answer:
Hi dear again.
A dominant allele (part of e chromosome) produces a dominant phenotype in individuals who have one copy of the allele, which can come from just one parent.

For recessive allele to produce e recessive phenotype the individual must have two copies, one from each parent.
Whether an allele is dominant or recessive depends on the particular of the process they code for.

I live in Albania so I don't know any geneticist in your country.

Hope I was helpful.

Regards Dr.Vjollca
Above answer was peer-reviewed by : Dr. Vinay Bhardwaj
doctor
default
Follow up: Dr. Vjollce Mbiarra (15 hours later)
hi,

As you mentioned that it will be difficult to Keep the pregnancy for 9 months, do you mean i could have a premature labor? or miscarriage?
doctor
Answered by Dr. Vjollce Mbiarra (45 minutes later)
Brief Answer:
You haven't increase chances for miscarriage

Detailed Answer:
Hi dear again.

No, you haven't increase chances for miscarriages or premature labor.
But I have mentioned that pregnancy can deteriorate Larsen syndrome. As per studies chances of fetal anomalies are there.
In my experience I haven't had any pregnant women with Larsen syndrome.
Hence prior to any pregnancy advice with your follow up doctor to see if your syndrome can make you a mother.

All the best

Above answer was peer-reviewed by : Dr. Bhagyalaxmi Nalaparaju
doctor
Answered by
Dr.
Dr. Vjollce Mbiarra

OBGYN, Maternal and Fetal Medicine

Practicing since :2006

Answered : 1572 Questions

premium_optimized

The User accepted the expert's answer

Share on

Get personalised answers from verified doctor in minutes across 80+ specialties

159 Doctors Online

By proceeding, I accept the Terms and Conditions

HCM Blog Instant Access to Doctors
HCM Blog Questions Answered
HCM Blog Satisfaction
Can Larsen Syndrome Cause Any Complications In Future Pregnancies?

Brief Answer: There is no problem getting or being pregnant Detailed Answer: Hi dear and thanks for your query. I understand your concern and I will try to help you. Larsen syndrome is a rare syndrome that have relation especially with Bones(bones dislocation) Women with this syndrome have no problem getting or being pregnant but Keeping pregnancy for 9 months may be difficult. Another problem for women with Larsen syndrome is that this syndrome can be transmitted in children and this vary, what type of defect do you have, is recesive or dominant. As per your symptoms, it may be recesive. Hence you are free to be pregnant and consult with an geneticist to calculate chances that you have to transmit Larsen syndrome in your future children. Feel free to discuss any other questions. All the best