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Dr. Andrew Rynne
MD
Dr. Andrew Rynne

Family Physician

Exp 50 years

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What Is The Remedy For Depression When On Wellbutrin?

I was just prescribed .5 mg or 1/2 tab of Lexapro to augment the use of Willbutrin SR 150mg (bid) Have taken Wellbutrin for at least 10 years and it has been the only anti-depressant that was effective. d/t many circumstances and stressors, my depression became worse this year. My Psychiatrist recently prescribed Lexapro to augment Wellbrurin (started at .25 mg (1/4 tab) x 1 week, then went to 1/2 mg which I am now on. My question #1) is, b/c it has made me drowsy during the day, could I take it h.s. and perhaps not experience the daytime drowsiness. Question 2) In the past, I usually have a glass of wine at dinnertime or one lager ale. All the literature I have read says that ETOH is not safe with Lexapro.. I had my annual P.E. this week and am in good health. Thanks for any advice you can give me.
Mon, 3 Mar 2014
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General & Family Physician 's  Response
Hello. Thank you for your question.... it is a good one!

First, I would like to clarify the Lexapro dosage. The lowest dose manufactured is a 5 mg tablet... so perhaps when you say 0.5 mg you really mean 5 mg?

In any case, it is perfectly okay, and in fact wise, to take your Lexapro at bedtime.

Regarding the ETOH.... nearly every medicine in the mental health realm has a warning about alcohol. To be honest, in the real world (or perhaps a world where lawyers don't exist), it is likely to be perfectly safe to drink one 4-6 oz glass of wine or 12 oz lager ale at dinnertime; especially if you are already doing so along with the medications, and experiencing no issues.

Best of Luck.... and hope this answer helps.
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What Is The Remedy For Depression When On Wellbutrin?

Hello. Thank you for your question.... it is a good one! First, I would like to clarify the Lexapro dosage. The lowest dose manufactured is a 5 mg tablet... so perhaps when you say 0.5 mg you really mean 5 mg? In any case, it is perfectly okay, and in fact wise, to take your Lexapro at bedtime. Regarding the ETOH.... nearly every medicine in the mental health realm has a warning about alcohol. To be honest, in the real world (or perhaps a world where lawyers don t exist), it is likely to be perfectly safe to drink one 4-6 oz glass of wine or 12 oz lager ale at dinnertime; especially if you are already doing so along with the medications, and experiencing no issues. Best of Luck.... and hope this answer helps.