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Dr. Andrew Rynne
MD
Dr. Andrew Rynne

Family Physician

Exp 50 years

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What Is 66 SGPT?

what is 66 SGPT? is it so serious? I am taking took lipitor for slightly elevated Cholesterol levels and Metformin for diabetis? Now cholesterol is 190 but triglycerides are 300. Just 6 months back i had triglycerides of 145. i have no bad health symptoms except little body pains in evening due to work strain.
Wed, 2 Sep 2015
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Cardiologist 's  Response
Hello. Thank you for your question and welcome to HCM. I understand your concern.

Both lipitor and metformin have the side effect that can raise the liver function tests, such as SGPT and SGOT. But these levels are not worrisome, since it has to be threefold from normal to be considered as a damaging effect of these drugs, and an indication for one of them or both to be discontinued, and be sought for other compatible diseases appropriate treating drugs. Even though these are not worrisome figures, I would recommend you to run blood liver function test levels again after two or three months, to see if these figures are steady or have a tendency to increase.

About the triglycerides: they are the fraction of the total lipid panel, that best reflect the last meal eating. If these changes are noted in a six months period, then I would assume that the test was run after you had eaten. Ideally, triglycerides should always be measured after a 24-hour fasting period. But, it is acceptable also that they get measured after a 16-hour fasting period. My recommendation is that you should consume more fibres in diet - green or dark green leafy vegetables, and fruit, up to 200-300 g a day, 60-minute physical activity a day and limit your alcohol intake (if you drink). I would suggest that, when you run the liver function tests, you should also run triglyceride levels. If they persist to be high, then a drug from the fibrate class can be added to your therapy.

I hope this answers your question.

Best regards,
Dr. Meriton
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What Is 66 SGPT?

Hello. Thank you for your question and welcome to HCM. I understand your concern. Both lipitor and metformin have the side effect that can raise the liver function tests, such as SGPT and SGOT. But these levels are not worrisome, since it has to be threefold from normal to be considered as a damaging effect of these drugs, and an indication for one of them or both to be discontinued, and be sought for other compatible diseases appropriate treating drugs. Even though these are not worrisome figures, I would recommend you to run blood liver function test levels again after two or three months, to see if these figures are steady or have a tendency to increase. About the triglycerides: they are the fraction of the total lipid panel, that best reflect the last meal eating. If these changes are noted in a six months period, then I would assume that the test was run after you had eaten. Ideally, triglycerides should always be measured after a 24-hour fasting period. But, it is acceptable also that they get measured after a 16-hour fasting period. My recommendation is that you should consume more fibres in diet - green or dark green leafy vegetables, and fruit, up to 200-300 g a day, 60-minute physical activity a day and limit your alcohol intake (if you drink). I would suggest that, when you run the liver function tests, you should also run triglyceride levels. If they persist to be high, then a drug from the fibrate class can be added to your therapy. I hope this answers your question. Best regards, Dr. Meriton