Hi Dr. Purushottam welcomes you to HCM virtual clinic. I have gone through your query. I think I have understood your concern, I will try to suggest you the best possible treatment options. First of all let me tell you that in the midst of all the problems, it s good to hear that Chromosome reports are normal- i think you are talking about your and your wife s reports. Secondly medical studies show that recurrence rate is 2-4% in next pregnancy depending on heart problem. But if 2 prior children are affected risk of recurrence rises to 10%. Only medical advice is to go for pre conception counseling- Use of Folic acid, Vit B12, micro nutrient supplementation from 3 months before planning pregnancy. Rubella vaccine shot, 3 months before planning pregnancy. I am sorry to say but , doing baby s 2 D echo and color Doppler by expert cardiologist, at 16,18, 22 weeks is what we can do just to detect it at the earliest. I hope my answer helps you. Thanks.