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Dr. Andrew Rynne
MD
Dr. Andrew Rynne

Family Physician

Exp 50 years

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What Causes Persistent Fever In A 22 Month Old?

hi my baby is 22 months old he got fever for 7 days continuiosly then a widal test was done it showed she was o:180 and h: 1:80 a negative b negetive doc prescribed zo 50 for two weeks after that we came back to our home town and went to her regular doc hesaid there are no traces of typhond asked to do a blood test done we got that done and report says negative now doctor askd to discontinue zo 50 my question is the 2nd blood test was done wen she was on zo is that the reason the second reportcameas negative ? and should i discontinue zo50? my baby s weight is 11.2 kg and she is still gettinver in 12 hours duration .. fever is around 100--101
Thu, 6 Oct 2016
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Pediatrician 's  Response
hi madam, The Widal test is unreliable but is widely used because of its low cost. but is not specific and false positives may occur. Acute- and convalescent-phase titers are more sensitive than a single serum sample. the diagnosis is based on clinical picture , blood / bone marrow cultures.
if you are living in area which is epidemic in typhoid infections , and no other diagnosis is possible by physical exam and history and blood and bone marrow cultures are not available I suggest starting on injectable 3rd generation Cephalosporin instead of ofloxacin ( zo50) because typhoid has resistance to this antibiotic , keeping in mind that fever may remain 3-5 days even during the treatment .
I hope this helps
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What Causes Persistent Fever In A 22 Month Old?

hi madam, The Widal test is unreliable but is widely used because of its low cost. but is not specific and false positives may occur. Acute- and convalescent-phase titers are more sensitive than a single serum sample. the diagnosis is based on clinical picture , blood / bone marrow cultures. if you are living in area which is epidemic in typhoid infections , and no other diagnosis is possible by physical exam and history and blood and bone marrow cultures are not available I suggest starting on injectable 3rd generation Cephalosporin instead of ofloxacin ( zo50) because typhoid has resistance to this antibiotic , keeping in mind that fever may remain 3-5 days even during the treatment . I hope this helps