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What Causes High Levels Of IGE With Asthma?
My son is 3 years old, will be 4 in January. He has had medical problems his whole life, was very delayed and still is to a certain extent, He has very severe asthma and has been hospitalized many times for asthma exaserbation... His pulminologist did a bllod allery test in September2010 and his IGE level at that time was 571, about 2 weeks ago we were shipped off to the hospital again for asthma exaserbation and spent 7 days in Kosair childrens hospital. A week before being sent to Louisville, ky we were referred to a pedatrice allergy doctor for the scratch test to check for allergies, but absolutely nothing showed up... The doctor redone the blood allergy test and yesterday we got the results and his number has went from 571 to 992... I have seched the internet and cannot seem to find any answers for what causes this level to be so high... I was instucted to take him to his doctor here at home to have his spleen and liver checked and tomorrow morning we have to get an ultrasound to see if either is enlarged... I have been trying to find answers for years to see what causes all of my sons problems... He also has epilepsy and has bowl problems, hard stools and has to take miralax to help him go sometime.... My main concern at this time is to figure out what this number means and why it is so high!!! If you could help at all I would greatly appreciate it! Thank you Melissa Cameron
Wed, 8 Apr 2020
Hi,
From what you said he has some delay in development, epilepsy and constipation- these 3 are interrelated- epilepsy and constipation are very common in delayed children, and we can control with anti-epileptics and laxatives as he might already been on.
The main worry now seems to be asthma and high IgE levels. Asthma basically is an allergic disorder. Some has intrinsic asthma (allergy not related to environmental allergens but part of our inherent body habit) and some have extrinsic one(allergy to environmental allergens like dust, pollen, certain food). Extrinsic one can be controlled if we can identify and eliminate the trigger, but intrinsic is somewhat difficult- here our body over reacts to minute insults / triggers because of inherent characteristics which we cannot alter much.
In both types, IgE will be high and symptoms can be managed with inhalers and certain drugs. Treatment is a step wise process needing regular followups and gradual up-gradation of treatment depending on the level of control.
Meanwhile take care of few things- avoid dust, tobacco / other smokes, playing in cold environment, feather, woollen clothes etc. Keep the bedroom free of dust. Use wet mopping for cleaning. strictly adhere to treatment protocol advised.
Hope I have answered your question. Let me know if I can assist you further.
Regards,
Dr. Muhammed Aslam TK, Pediatrician
From what you said he has some delay in development, epilepsy and constipation- these 3 are interrelated- epilepsy and constipation are very common in delayed children, and we can control with anti-epileptics and laxatives as he might already been on.
The main worry now seems to be asthma and high IgE levels. Asthma basically is an allergic disorder. Some has intrinsic asthma (allergy not related to environmental allergens but part of our inherent body habit) and some have extrinsic one(allergy to environmental allergens like dust, pollen, certain food). Extrinsic one can be controlled if we can identify and eliminate the trigger, but intrinsic is somewhat difficult- here our body over reacts to minute insults / triggers because of inherent characteristics which we cannot alter much.
In both types, IgE will be high and symptoms can be managed with inhalers and certain drugs. Treatment is a step wise process needing regular followups and gradual up-gradation of treatment depending on the level of control.
Meanwhile take care of few things- avoid dust, tobacco / other smokes, playing in cold environment, feather, woollen clothes etc. Keep the bedroom free of dust. Use wet mopping for cleaning. strictly adhere to treatment protocol advised.
Hope I have answered your question. Let me know if I can assist you further.
Regards,
Dr. Muhammed Aslam TK, Pediatrician
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