Hi, Sertraline HCL is an antidepressant medication that is used to treat the major depressive disorder, obsessive-compulsive disorder, panic disorder, post-traumatic stress disorder, social anxiety disorder, and premenstrual dysphoric disorder. Some of the possible side effects of sertraline HCL include nausea, diarrhea, constipation, headache, dizziness, drowsiness, insomnia, dry mouth, sweating, changes in appetite or weight, and sexual dysfunction. Divalproex ER is a medication used to treat bipolar disorder, epilepsy, and migraines. Some of the possible side effects of divalproex ER include nausea, vomiting, diarrhea, constipation, headache, dizziness, drowsiness, blurred or double vision, hair loss, weight changes, tremors, swelling of the hands, feet, or ankles, changes in menstrual periods, decreased sex drive, and impotence. It is important to note that suicidal thoughts and behavior can occur in people taking antidepressant medication, especially in the first few weeks of treatment or when the dose is changed. Seek immediate medical attention if your brother expresses suicidal thoughts or behavior. Additionally, hearing voices can be a symptom of a serious mental health condition, and your brother needs to receive appropriate treatment and support from a mental health professional. Take care. Hope I have answered your question. Let me know if I can assist you further. Regards, Dr. Priyanka, General & Family Physician