Hi, Cremaffin is a laxative that is commonly used to relieve constipation and prevent anal fissures. The recommended dosage of Cremaffin varies depending on the severity of constipation or anal fissure. While Cremaffin is generally considered safe, prolonged use can lead to side effects such as electrolyte imbalances, dehydration, and dependence on the medication for bowel movements. Additionally, overuse of Cremaffin can lead to diarrhea, abdominal pain, and cramping. It is important to talk to your doctor before using any medication for an extended period, especially if you are experiencing side effects. Your doctor may recommend other treatments for your anal fissure, such as dietary changes, stool softeners, or surgery, to address the underlying cause of your symptoms. Take care. Hope I have answered your question. Let me know if I can assist you further. Regards, Dr. Priyanka, General & Family Physician