Greetings ! Well both wellbutin and cipralex are good anti depressants and relatively safe in terms of side effects but wellbutrin or better will be wellbutrin xl ( long acting evrsion fo wellbutrin) is the most safe anti depressant out of all its peers and it has good affect on depression as well. It does not cause sexual side effects like delayed ejaculation and erection problem and does not cause weight gain , these side effects being caused by cipralex. Wellbutrin l also has better affect on fatigue and boosts one s energy levels and increases concentration and alertness. So wellbutrin xl has an edge over cipralex in terms of safety and side effects but it is slightly less effective as compared to cipralex against depression, so wellbutrin xl is a better choice for you. I hope this helps. Regards