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Dr. Andrew Rynne
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Dr. Andrew Rynne

Family Physician

Exp 50 years

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What Are Hepatitis B Vaccines And How Do We Know They Are Effective ?

my brother has taken 4doses of hep b vac..how should i know it has working or not...and how can we find useable and unusable vac..is there any changes in liquid..?
Wed, 1 Feb 2012
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Orthopaedic Surgeon,  's  Response
Welcome to Healthcare Magic
Typically three doses with one or two booster doses is recommended. You cannot tell by just looking if the fluid has been used but that is not a matter of concern. If the blue square has turned dark as the colour of the dark surrounding circle then it could be ineffective. This is a sticker seen on the vaccine vial in some countries like India. You can get your HBsAg serum levels estimated to know your protection level if more than 10IU/L it is safe.
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General & Family Physician,  Dr. Pavan Kumar Gupta's  Response
Hello.Welcome to HCM forum.Only three doses of vaccine are given at 0,1and 6 months.Whether your vaccine is giving you protection or not can be found out by measuring ant-HBs and not HBsAg.The values of anti-HBs should be more than 10 IU/ml.Any person who is previously vaccinated is found to have anti-HBs less than 10 IU/ml should be given a booster dose of HEP-B Vaccine.Don't use the vaccine if found to have some suspended particles or if it's color has changed.Thanks and good luck.
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What Are Hepatitis B Vaccines And How Do We Know They Are Effective ?

Welcome to Healthcare Magic Typically three doses with one or two booster doses is recommended. You cannot tell by just looking if the fluid has been used but that is not a matter of concern. If the blue square has turned dark as the colour of the dark surrounding circle then it could be ineffective. This is a sticker seen on the vaccine vial in some countries like India. You can get your HBsAg serum levels estimated to know your protection level if more than 10IU/L it is safe.